Prognosis and Risk Factors of Sepsis Patients in Chinese ICUs: A Retrospective Analysis of a Cohort Database

Conclusions: Patients with hypotension but without hyperlactacidemia in the ICU also show a high 28-day mortality, and some clinical factors may affect their prognosis and must be treated carefully in the future.
Source: Shock - Category: Emergency Medicine Tags: Clinical Science Aspects Source Type: research

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In conclusion, the treatment responses of immunotherapy, either alone or in combination with other therapies, were highly variable in patients with ATC and should be carefully monitored along with the side effects.PMID:35031200 | DOI:10.1016/j.jfma.2022.01.003
Source: J Formos Med Assoc - Category: General Medicine Authors: Source Type: research
J Natl Compr Canc Netw. 2022 Jan;20(1):45-53. doi: 10.6004/jnccn.2021.7046.ABSTRACTBACKGROUND: To describe short-term outcomes and independent predictors of 28-dayx mortality in adult patients with hematologic malignancies and septic shock defined by the new Third International Consensus Definitions (Sepsis-3) criteria.METHODS: We performed a retrospective cohort study of patients admitted to the medical ICU with septic shock from April 2016 to March 2019. Demographic and clinical features and short-term outcomes were collected. We used descriptive statistics to summarize patient characteristics, logistic regression to ide...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - Category: Cancer & Oncology Authors: Source Type: research
We report that whereas microglia are characterized by marked gene-level alterations related to negative regulation of protein phosphorylation and phagocytic vesicles, astrocytes show activation of enzyme- or peptidase-inhibitor signaling after detectable changes in BBB permeability. We also identify several genes enriched in these pathways that are notably altered after BBB breakdown. Our data reveal that microglia and astrocytes play an active role in maintaining BBB stabilization and corralling infiltrating cells, and thus might potentially function in ameliorating the lesions and neurologic disabilities in CNS diseases....
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This video shows a case of nasal myiasis under fibreoptic bronchoscopic visualization in a patient admitted with septic shock and metastatic prostate cancer. Key messageThis is a video showing a case of nasal myiasis under direct visualization with flexible bronchoscopy in a patient admitted with septic shock and metastatic prostate cancer. Microbiology revealedLucilia sericata larvae.
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: CLINICAL VIDEO Source Type: research
World J Gastroenterol. 2021 Nov 28;27(44):7582-7596. doi: 10.3748/wjg.v27.i44.7582.ABSTRACTHypothalamic neuropeptides named hypocretin/orexins which were identified in 1998 regulate critical functions such as wakefulness in the central nervous system. These past 20 years had revealed that orexins/receptors system was also present in the peripheral nervous system where they participated to the regulation of multiple functions including blood pressure regulation, intestinal motility, hormone secretion, lipolyze and reproduction functions. Associated to these peripheral functions, it was found that orexins and their receptors...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
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