Lyme disease

Lyme disease is the most common tick-borne illness in the USA and Europe. Pathogens involved include Borrelia burgdorferi in the USA and B. afzelii and B. garinii in Europe. The characteristic rash of erythema migrans occurs in 70 –80% of patients. Neurological disease, including facial palsy, meningo-encephalitis, aseptic meningitis and polyradiculopathy, occurs in 10–15%. Cardiac disease, primarily manifest as heart block, is seen in 1–4%. Arthritis is a late complication in about 30% of untreated patients.
Source: Medicine - Category: Internal Medicine Authors: Tags: Bacterial infections Source Type: research

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Conclusions Fascia lata and Strattice slings provide satisfactory results in restoring symmetry at rest and functional oral competence. Our results suggest that Strattice is a safe sling material with an acceptable risk profile and comparable medium-term maintenance of tensile strength to fascia lata, and should be considered where life expectancy, donor site morbidity, and procedure length are important considerations.
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Peripheral Nerve Surgery and Research Source Type: research
CONCLUSION: Taken together, our results demonstrated that MF would be a promising anti-arthritic agent candidate for further research.PMID:34836794 | DOI:10.1016/j.intimp.2021.108352
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Source Type: research
Autoimmune encephalitis (AE) with multiple auto-antibodies is of great clinical significance because its complex clinical manifestations and atypical imaging increase the difficulty of diagnosis, differential ...
Source: BMC Neurology - Category: Neurology Authors: Tags: Case report Source Type: research
Dabieshan tick virus (DTV) was first identified in Haemaphysalis longicornis from Hubei Province, China in 2015. However, its pathogenic potential to animals and human remains to be further explored. In this stud...
Source: Virology Journal - Category: Virology Authors: Tags: Short report Source Type: research
ConclusionThese results provide evidence that DNA bound to HLA class II molecules is involved in SLE pathogenesis.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Brief Report Source Type: research
Abstract: The aim of this analysis was to re-examine the classical concept of distal interphalangeal joint (DIP) psoriatic arthritis (PsA) as an entheseal-driven disease. Two cadaveric fingers with severe psoriatic arthritis were analyzed. Our results demonstrate that inflammation of DIP PsA is multifocal without interconnection between entheses and articular cartilage of the DIP. We found a clear association between synovitis and focal loss of articular cartilage at the head of the intermediate phalanx. By contrast, the articular cartilage adjacent to the zone of severe enthesitis did not show notable damage. Fibrocar...
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Original Study Source Type: research
Tibiotalocalcaneal arthrodesis is a salvage procedure for severe ankle and hindfoot deformities, cases with bone loss, arthritis, and failed previous surgeries. Complex situations leave the surgeon apprehensive over large bone defects. Several options to bridge the bone gap have been described; however, the easy availability of allografts and cages poses a significant challenge for the less privileged surgeon. Here we describe a simple indigenous technique of utilizing autologous fibula to bridge large bone defects between the tibia and calcaneus during tibiotalocalcaneal fusion. The technique has advantages like the gener...
Source: Techniques in Foot and Ankle Surgery - Category: Orthopaedics Tags: Techniques Source Type: research
No abstract available
Source: Lippincott's Bone and Joint Newsletter - Category: Orthopaedics Tags: Snapshot Source Type: news
No abstract available
Source: Nursing - Category: Nursing Tags: Department: INFECTION PREVENTION Source Type: research
AbstractCOVID-19 is associated with encephalitis in critically ill patients and endothelial dysfunction seems to contribute to this life-threatening complication. Our objective was to determine the hallmark of endothelial activation in COVID-19 related encephalitis.In an observational study in intensive care unit (ICU), we compared vascular biomarkers of critically ill COVID-19 patients with or without encephalitis. To be classified in the Encephalitis group, patients had to have new onset of central neurologic symptom, and pathological findings on either brain magnetic resonance imaging (MRI) and/or electroencephalogram (...
Source: Journal of Neurochemistry - Category: Neuroscience Authors: Tags: ORIGINAL ARTICLE Source Type: research
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