Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administered Ruxolitinib and Artemether-Lumefantrine in Healthy Adults

This study supports the investigation of the combination of artemether-lumefantrine and ruxolitinib in healthy volunteers infected with Plasmodium falciparum malaria. (This study has been registered at ClinicalTrials.gov under registration no. NCT04456634).PMID:34694880 | DOI:10.1128/AAC.01584-21

Source: Antimicrobial Agents and Chemotherapy - October 25, 2021 Category: Microbiology Authors: M Farouk Chughlay Karen I Barnes Myriam El Gaaloul Nada Abla J örg J Möhrle Paul Griffin Paul van Giersbergen Stephanie E Reuter Hayley B Schultz Anita Kress Peter Tapley Rebecca A Webster Timothy Wells James S McCarthy Bridget E Barber Louise Marquart Source Type: research