The impact of methamphetamine/amphetamine use on receipt and outcomes of medications for opioid use disorder: a systematic review

CONCLUSIONS: Overall, existing research suggests people who use methamphetamine/amphetamines may have lower receipt of MOUD, retention in MOUD, and opioid abstinence during MOUD. Future research should examine how specific policies and treatment models impact MOUD outcomes for these patients, and seek to understand the perspectives of MOUD providers and people who use both opioids and methamphetamine/amphetamines. Efforts to improve MOUD care and overdose prevention strategies are needed for this population.PMID:34635170 | DOI:10.1186/s13722-021-00266-2
Source: Addiction Science and Clinical Practice - Category: Addiction Authors: Source Type: research

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CONCLUSIONS: PST, which can be made through purchase of readily available poppy pods, carries risk for development of OUD and overdose. Herein we highlight the utility of a primary care opioid prescribing support team in empowering a primary care provider to prescribe BUP to treat a patient with complex OUD.PMID:34861895 | DOI:10.1186/s13722-021-00280-4
Source: Addiction Science and Clinical Practice - Category: Addiction Authors: Source Type: research
Conclusions: Low-threshold OAT was at least as effective and safe as the standard OAT in terms of treatment retention, the use of illicit opioids, non-fatal overdose, and death. Healthcare utilization increased during the OAT compared to the period before. Lowering the threshold for OAT entrance within proper delivery platforms should be broadly considered to reduce harm and improve healthcare access among patients with opioid dependence.Eur Addict Res
Source: European Addiction Research - Category: Addiction Source Type: research
World J Biol Psychiatry. 2021 Dec 2:1-19. doi: 10.1080/15622975.2021.2012397. Online ahead of print.ABSTRACTPharmacogenetic investigations into the opioid crisis suggest genetic variation could be a significant cause of opioid- related morbidity and mortality. Variability in opioid system genes, including single nucleotide polymorphisms, manifest after pharmacogenetic testing, as previously invisible risk factors for addiction and overdose. Pharmacodynamic genes regulate opioid-sensitive brain networks and neural reward circuitry. Pharmacokinetic genes expressed in drug metabolic pathways regulate blood levels of active ve...
Source: The World Journal of Biological Psychiatry - Category: Psychiatry Authors: Source Type: research
The centers provide people a place to bring their drugs and use them under the supervision of trained staff members who will provide clean needles, prevent overdoses and offer connections to addiction services.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Jeffrey A. SingerSarah Wakeman, MD is the Medical Director of the Massachusetts General Hospital Substance Use Disorder Project and an Associate Professor of Medicine at Harvard University Medical School. She has a wealth of experience treating addiction and has published research on thecomparative effectiveness of various treatment modalities for opioid use disorder.Dr. Wakeman recently gave aninterview to theHarvard Gazette in response to therecent news that overdose deaths for the 12 months ending April 30, 2021 reached a stunning 100,000, 75 percent of which were opioid ‐​related, with 85 percent of opioi...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
BACKGROUND: Illicitly manufactured fentanyl (IMF) is increasing in international drug supply chains, and IMF-related opioid overdose deaths are rising in North America. Hospitalizations among patients with opioid use disorder (OUD) are also rising; and, ho...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Addict Behav. 2021 Nov 14:107182. doi: 10.1016/j.addbeh.2021.107182. Online ahead of print.ABSTRACTRates of injection drug use (IDU) of opioids have been consistently lower among Black people relative to Non-Hispanic White people despite rising IDU estimates. While explanations have been proposed, no study has explored differences within a clinical sample of Black people in treatment who prefer IDU to non-IDU opioid administration. The purpose of this pilot study was to explore these differences guided by a seminal framework (e.g., market force, social network, and risk-taking characteristics), along with mental health sym...
Source: Addictive Behaviors - Category: Addiction Authors: Source Type: research
Conclusion: The increase in overall mortality rate because of stimulants use reflects the increase of MA use in this age group. The difference in the rate of change shows worsening racial inequality. Public health policies should be implemented to include evidence-based strategies to prevent MA misuse or overdose.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Jeffrey A. SingerOn November 18 theWall Street Journalran a front page story entitled “Drug Overdose Deaths, Fueled by Fentanyl, Hit Record High in U.S. ” It reported on provisional data from the Centers for Disease Control and Prevention that reveal a heartbreaking 100,306 drug overdose deaths for the 12 months running through April 2021, a 29 percent increase over the previous 12 month period.Thereport released by the CDC on November 17 stated that 75,673 of the more than 100,000 overdose deaths were opioid ‐​related, up from 56,064 the previous year. The remainder of overdose deaths involv...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
Drug overdoses killed more than 100,000 people in the United States during the one-year period ending in April 2021, according toprovisional data issued yesterday by the Centers for Disease Control and Prevention (CDC). This marks the first time that drug overdose deaths reached six figures in one year and represents a 29% increase in overdose deaths from the prior year.Synthetic opioids (that mimic the effects of natural opioids like heroin but are far more potent), primarily fentanyl, were responsible for 64% of the total deaths, a rise of nearly 50% from the year before, according to the CDC ’s National Center for...
Source: Psychiatr News - Category: Psychiatry Tags: CDC drug overdose fentanyl methamphetamine pandemic Source Type: research
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