Methadone-related death in detention - Flanagan RJ, Shepherd RT.
Oral methadone may be prescribed to detainees with the aim of minimising the risk of fatal opioid poisoning on release. To study the circumstances under which methadone-related deaths can occur in detention, we audited reports of 17 [14 male, 3 female; med... (Source: SafetyLit)
Source: SafetyLit - May 4, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Xylazine, a Dangerous Veterinary Tranquilizer, Is Showing Us the Future of the Overdose Crisis
There’s a new drug beginning to spread rapidly through the street drug supply of the United States: Xylazine, an animal tranquilizer, increasingly used as a synthetic cutting agent for opioids like heroin. We recently published a study, based on years of research across the U.S., which found that xylazine is popping up in cities all over the country. Use of the drug is increasing at exponential rates where it lands, causing outbreaks of skin infections and overdoses. The national spread of xylazine is a public health threat. It also foreshadows the future of the overdose crisis—increasingly driven by powerful s...
Source: TIME: Health - April 6, 2022 Category: Consumer Health News Authors: Joseph Friedman and Philippe Bourgois Tags: Uncategorized health healthscienceclimate Source Type: news

Structural violence and the need for compassionate use of methadone in Mexico - Romero-Mendoza M, Pel áez-Ballestas I, Almanza-Avendaño AM, Figueroa E.
The objective of this study was... (Source: SafetyLit)
Source: SafetyLit - April 1, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Is high sensitive-troponin I a reliable biomarker for cardiac injury in methadone toxicity? A prospective cross-sectional study - Shemirani H, Sadeghi M, Dehkordi AD, Gheshlaghi F.
BACKGROUND: Methadone is a synthetic opioid mostly used for detoxification therapy, as its use increases; the possibility for methadone-induced cardiotoxicity may rise. The aim of this study was to determine the association of high-sensitivity troponin I l... (Source: SafetyLit)
Source: SafetyLit - March 28, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

What Euphoria Gets Right —and Wrong—About Teen Drug Use and Addiction
Euphoria—the most tweeted-about TV show of the decade in the U.S.—has thrust teenage drug use into the cultural spotlight. The HBO show follows 17-year-old Rue Bennett, a sweet but troubled teen played by Zendaya, as she navigates a deepening drug use disorder. It’s not pretty. Rue takes the powerful opioid fentanyl, injects morphine, and drags around a suitcase filled with thousands of dollars worth of drugs (a stash she can’t resist dipping into). Meanwhile, she rips apart her life: tearing through her house, ransacking strangers’ homes, and screaming at the people she loves the most. [time-...
Source: TIME: Health - February 28, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized Source Type: news

Methadone exposures reported to poison control centers in the United States following the COVID-19-related loosening of federal methadone regulations - Welsh C, Doyon S, Hart K.
BACKGROUND: Methadone is a highly effective treatment for opioid use disorder. Its use in the United States is highly regulated at both the federal and state level. The regulations related to take-home doses were loosened because of the 2019 Novel Coronavi... (Source: SafetyLit)
Source: SafetyLit - January 31, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Trends in and characteristics of drug overdose deaths involving illicitly manufactured fentanyls - United States, 2019-2020 - O'Donnell J, Tanz LJ, Gladden RM, Davis NL, Bitting J.
During May 2020-April 2021, the estimated number of drug overdose deaths in the United States exceeded 100,000 over a 12-month period for the first time, with 64.0% of deaths involving synthetic opioids other than methadone (mainly illicitly manufactured f... (Source: SafetyLit)
Source: SafetyLit - December 18, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Treatment for opioid dependence has an important role in suicide prevention
Opioid agonist treatment, commonly methadone or buprenorphine, for people dependent on heroin or other opioid drugs has an important role to play in suicide prevention, according to University of Bristol-led research published in The Lancet Psychiatry. (Source: University of Bristol news)
Source: University of Bristol news - December 16, 2021 Category: Universities & Medical Training Tags: Research, Health; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Population Health Sciences, Institutes, Bristol Population Health Science Institute; Press Release Source Type: news

Comparisons of injection and non-injection opioid use among Black people in methadone treatment: a pilot in Detroit - Struble CA, Lister JJ, Urbiel J, Nyaku AN, Arfken CL.
Rates of injection drug use (IDU) of opioids have been consistently lower among Black people relative to Non-Hispanic White people despite rising IDU estimates. While explanations have been proposed, no study has explored differences within a clinical samp... (Source: SafetyLit)
Source: SafetyLit - November 30, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Public health risks associated with methadone in Iran: a systematic review and meta-analysis - Rostam-Abadi Y, Gholami J, Noroozi A, Ansari M, Baheshmat S, Hamzehzadeh M, Ghadirzadeh MR, Vahdani B, Ekhtiari H, Mojtabai R, Rahimi-Movaghar A.
BACKGROUND: There has been a marked growth in methadone maintenance treatment (MMT) in Iran in the past two decades with positive health outcomes. We conducted a systematic review of studies on the prevalence of non-prescribed methadone use, methadone use ... (Source: SafetyLit)
Source: SafetyLit - November 29, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Notes from the field: Testing for nonprescribed fentanyl and percentage of positive test results among patients with opioid use disorder - United States, 2019-2020 - Niles JK, Gudin J, Vivolo-Kantor AM, Gladden RM, Mustaquim D, Seth P, Kaufman HW.
Overdose deaths involving synthetic opioids excluding methadone (primarily illicitly manufactured fentanyl) have increased approximately tenfold since 2013 (1) and have accelerated during the COVID-19 pandemic, with provisional estimates indicating that sy... (Source: SafetyLit)
Source: SafetyLit - November 26, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Short-Acting Opioids Needed for Withdrawal in Hospitals: Experts Short-Acting Opioids Needed for Withdrawal in Hospitals: Experts
The short-acting drugs can complement methadone and buprenorphine to help patients get faster relief and help patients stay in the hospital to help with long-term management, say authors.Medscape Medical News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - November 23, 2021 Category: Emergency Medicine Tags: Internal Medicine News Source Type: news

Class 3 Medicines Recall: Martindale Pharma, an Ethypharm Group Company Methadone 5mg Tablets / Physeptone 5mg Tablets
Martindale Pharma is recalling a specified batch of methadone 5mg tablets as a precautionary measure due to the discolouration of the PVdC film in a small number of blister pockets. Further informati (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - November 22, 2021 Category: Drugs & Pharmacology Source Type: news

CMS: Medicare Program; Opioid Treatment Programs: CY 2022 Methadone Payment Exception
Notice of interim final rule with comment period from the Centers for Medicare and Medicaid Services (CMS) freezing the payment to Opioid Treatment Programs (OTP) for methadone in calendar year (CY) 2022 at the CY 2021 rate. CMS is seeking comment on this exception to the payment methodology for the drug component of an episode of care and OTP utilization patterns for methadone, particularly, the frequency with which methadone oral concentrate is used compared to methadone tablets in the OTP setting. Comments are due by January 3, 2022. These regulations are effective January 1, 2022. (Source: Federal Register updates via ...
Source: Federal Register updates via the Rural Assistance Center - November 19, 2021 Category: Rural Health Source Type: news