Clinical characteristics and time trends of hospitalized methadone exposures in the United States based on the Toxicology Investigators Consortium (ToxIC) case registry: 2010-2017 - Mehrpour O, Hoyte C, Amirabadizadeh A, Brent J, Toxicology Investigators Consortium (ToxIC).
BACKGROUND: Methadone is well known for its long duration of action and propensity for mortality after an overdose. The present research was aimed at evaluating the clinical manifestations and time trends of methadone exposure in patients in US hospitals. ... (Source: SafetyLit)
Source: SafetyLit - July 27, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Travel Times to Opioid Addiction Programs Drive a Lack of Access Travel Times to Opioid Addiction Programs Drive a Lack of Access
Allowing pharmacies in the US to dispense methadone would significantly reduce the time involved in obtaining the medication and save money, new research shows.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - July 20, 2020 Category: Internal Medicine Tags: Psychiatry News Source Type: news

Patients with substance use disorder discriminated against by post-acute care facilities
(Boston Medical Center) A new study shows that 29 percent of private post-acute care facilities in Massachusetts explicitly discriminated against hospitalized individuals with opioid use disorder, rejecting their referral for admission. Led by researchers at Boston Medical Center's (BMC's) Grayken Center for Addiction, the study showed that 15 percent of the rejections among patients with substance use disorders were denied due to a substance use disorder diagnosis or because they were being treated for opioid use disorder with buprenorphine or methadone. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 16, 2020 Category: Infectious Diseases Source Type: news

Under 2% of Medicaid-covered youths get MAT after OD: study - Knopf A.
Fewer than one-third of youths receive addiction treatment after an opioid overdose, and only one in 54 receive pharmacotherapy (methadone, buprenorphine or naltrexone), a study published in JAMA Pediatrics reports. The researchers urge interventions to li... (Source: SafetyLit)
Source: SafetyLit - July 14, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Kenya: Recovering Drug Addicts in Kenya Find Treatment Difficult With COVID-19
[RFI] Covid-19 regulations in Kenya pose additional challenges to recovering drug addicts along the coastal areas, who say they are finding it difficult to access their methadone recovery programs due to an inter-county lockdown and dusk to dawn curfew. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 6, 2020 Category: African Health Source Type: news

Methadone-related deaths among youth and young adults in Sweden 2006-2015 - Fugelstad A, Bremberg S, Hjelmstr öm P, Thiblin I.
AIMS: To identify methadone-related deaths and determine the prevalence among youth and young adults in Sweden 2006-2015. DESIGN, SETTING AND PARTICIPANTS: National retrospective registry study comparing data from all forensic autopsy examinations and ... (Source: SafetyLit)
Source: SafetyLit - June 17, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Meds2Go Express Pharmacy, Inc. Sentenced for Role in Drug Diversion Scheme
FDA OCI, Alum Creek WV, Meds2Go Express Pharmacy, drug diversion, sentencing, money laundering, conspiracy, Hope Clinic, pain clinic, pill mill, opioids, oxycodone, methadone, addicts, illegal manufacturing, restitution, forfeiture, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - June 3, 2020 Category: Medical Law Authors: DOJ Source Type: news

Relationship between Buddhist belief and suicide risk in Chinese persons undergoing methadone maintenance therapy for heroin dependence - Huang JX, Xu YM, Zhong BL.
BACKGROUND: In western countries, there is a negative association between religious belief and suicide risk, while in China this association is positive. Nevertheless, few data are available on the association between one specific type of religion and suic... (Source: SafetyLit)
Source: SafetyLit - June 3, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

US relaxes rules for opioid substitutes during lockdowns
Trump administration makes it easier for addicts to obtain methadone and other treatment drugs (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - May 28, 2020 Category: Pharmaceuticals Source Type: news

One-third of primary care physicians do not support the use of medications for treating opioid use disorders
(American College of Physicians) A survey of primary care physicians found that one-third did not perceive medications to treat OUD to be more effective than nonmedication treatment or safe for long-term use, despite conclusive evidence to the contrary. Physicians also reported low interest in treating OUD and low support for policy proposals allowing office-based physicians to prescribe buprenorphine and methadone. These findings are reported in a brief research report published in Annals of Internal Medicine. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 20, 2020 Category: International Medicine & Public Health Source Type: news

Coronavirus: Recovering heroin addicts offered monthly injections
Daily trips to the pharmacy for methadone are replaced with monthly buprenorphine injections. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - April 18, 2020 Category: Consumer Health News Source Type: news

Impact of pharmacological treatments for opioid use disorder on mortality - Kelty E, Hulse G, Joyce D, Preen DB.
The use of pharmacological treatments for opioid use disorders, including methadone, buprenorphine and naltrexone has been associated with a reduction in mortality compared with illicit opioid use. However, these treatments can also contribute significantl... (Source: SafetyLit)
Source: SafetyLit - March 31, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Flawed studies distort risk of opioid addiction treatment while pregnant
Studies that assess risks to pregnant women undergoing treatment for opioid addiction may have significant flaws that overstate the impact of drugs like buprenorphine and methadone on child development. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 19, 2020 Category: Consumer Health News Source Type: news

Drug and Opioid-Involved Overdose Deaths - United States, 2017-2018
From 2017 to 2018, U.S. overdose death rates involving synthetic opioids (excluding methadone) increased by 10%, death rates involving heroin decreased by 4%, and prescription opioid-involved overdose death rates decreased by 13.5%. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - March 19, 2020 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Overdose Prescription Drug Abuse Synthetic Opioids Source Type: news

FAQs: Provision of Methadone and Buprenorphine for the Treatment of Opioid Use Disorder in the COVID-19 Emergency
Source: Substance Abuse and Mental Health Services Administration (SAMHSA). Published: 3/19/2020. This two-page document provides answers to frequently asked questions about providing methadone and buprenorphine for the treatment of opioid use disorder during the COVID-19 (coronavirus) epidemic. Topics include the use of telehealth for new and existing patients, and dispensing medication based on telehealth. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - March 19, 2020 Category: International Medicine & Public Health Source Type: news

6 Italian inmates die during protest over virus measures
They died after breaking into the infirmary and overdosing on methadone. (Source: ABC News: Health)
Source: ABC News: Health - March 9, 2020 Category: Consumer Health News Tags: Health Source Type: news

Italy: 6 inmates protesting virus restrictions die after breaking into prison infirmary, overdosing on methadone
(Source: ABC News: Health)
Source: ABC News: Health - March 9, 2020 Category: Consumer Health News Tags: Health Source Type: news

Methadone poisonings: a seven-year retrospective study of the French poison center network focusing on suicide attempt vs. misuses - Franchitto N.
This editorial refers to the article ‘Methadone poisonings: a seven‐year retrospective study of the French poison center network focusing on suicide attempt vs. misuses’ by Romain Torrents et al. published in Fundamental and Clinical Pharmacology... (Source: SafetyLit)
Source: SafetyLit - March 7, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

New Data Strongly Support Opioid Agonists for Addiction New Data Strongly Support Opioid Agonists for Addiction
New research provides strong support that opioid agonists, methadone, or buprenorphine cut the risk of overdose death by 80%, yet many addiction programs don't offer them.Medscape Medical News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - February 28, 2020 Category: Emergency Medicine Tags: Psychiatry News Source Type: news

Anti-Addiction Meds Key to Saving Lives of People Hooked on Opioids
TUESDAY, Feb. 25, 2020 -- People treated for an opioid addiction stand a much better chance of breaking their dependency if they take opioid-blocking medications, a new study finds. In fact, addicts who took methadone or buprenorphine had an 80%... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 25, 2020 Category: General Medicine Source Type: news

Medication Treatment May Lower Risk for Opioid Overdose Death
TUESDAY, Feb. 25, 2020 -- Medication treatment with methadone and buprenorphine is associated with a significantly lower risk for overdose death for people with opioid use disorder (OUD) compared with nonmedication treatment, but this lower risk... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 25, 2020 Category: Pharmaceuticals Source Type: news

Medication treatments led to 80% lower risk of fatal overdose for patients with opioid use disorder
(NYU Langone Health / NYU School of Medicine) Patients with opioid use disorder (OUD) receiving treatment with opioid agonists (medications such as methadone or buprenorphine) had an 80 percent lower risk of dying from an opioid overdose compared to patients in treatment without the use of medications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2020 Category: International Medicine & Public Health Source Type: news

Mortality decreased with further treatment for opioid use disorder after detox
(Boston Medical Center) A new study shows that people with opioid use disorder who enter inpatient medically managed withdrawal treatment (detox) do not usually receive further treatment, including medication for opioid use disorder or additional inpatient treatment. Those who did receive further treatment with medication (methadone, buprenorphine or naltrexone) or residential treatment were more likely to survive to 12 months. Published in Addiction, this study emphasizes the importance of keeping people with opioid use disorder engaged in treatment in order to increase their chances of survival. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2020 Category: International Medicine & Public Health Source Type: news

Patients most at risk of overdose at the beginning and after end of methadone treatment
(RCSI) A new study, led by RCSI researchers, has found that patients receiving methadone treatment are most at risk of overdosing in the month following the end of methadone treatment and during the first four weeks of treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2020 Category: International Medicine & Public Health Source Type: news

Epidemiology of pediatric buprenorphine and methadone exposures reported to the poison centers - Rege SV, Ngo DA, Ait-Daoud N, Rizer J, Sharma S, Holstege CP.
BACKGROUND: Buprenorphine prescriptions have increased dramatically within the United States, whereas methadone continues to be used widely. We investigated the trends and characteristics of buprenorphine and methadone exposures in the pediatric population... (Source: SafetyLit)
Source: SafetyLit - January 31, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Low-Dose Gabapentin in Combination with Methadone May Improve QOL in Patients with HNC
Administering a high dose of gabapentin also increased the percentage of patients who required no opioid during treatment, indicating that patients were possibly gleaning benefits from gabapentin in both treatment arms. (Source: CancerNetwork)
Source: CancerNetwork - January 23, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Total Opioid Overdose Deaths Down With Medicaid Expansion
FRIDAY, Jan. 10, 2020 -- Medicaid expansion is associated with a reduction in total opioid overdose deaths and with increases in methadone-related mortality, according to a study published online Jan. 10 in JAMA Network Open. Nicole Kravitz-Wirtz,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 10, 2020 Category: Pharmaceuticals Source Type: news

Meds2Go Express Pharmacy, Inc. Pleads Guilty to Money Laundering in Connection with Drug Diversion Scheme
Alum Creek WV, Meds2Go Express Pharmacy, plea, guilty, money laundering, drug diversion, pain clinic, pill mill, opioids, community restitution, drug abuse treatment, Rx opioids, red flags, oxycodone, drug addicts, methadone, compounding, Charleston WV, forfeiture, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - January 6, 2020 Category: Medical Law Authors: DOJ Source Type: news

Yale study urges lifesaving drug treatment to combat Ukraine's HIV epidemic
(Yale University) A new study led by Yale University researchers finds that scaling up use of methadone and buprenorphine could greatly reduce HIV transmission rates and prevent deaths in Ukraine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 3, 2020 Category: International Medicine & Public Health Source Type: news

Study urges life-saving drug treatment to combat Ukraine ’s HIV epidemic
A new study finds that scaling up use of methadone and buprenorphine could greatly reduce HIV transmission rates and prevent deaths in Ukraine. (Source: Yale Science and Health News)
Source: Yale Science and Health News - January 2, 2020 Category: Universities & Medical Training Source Type: news

A comparison of blood toxicology in fatalities involving alcohol and other drugs in patients with an opioid use disorder treated with methadone, buprenorphine, and implant naltrexone - Kelty E, Hulse G, Joyce D.
Background: Methadone, buprenorphine, and implant naltrexone have comparable efficacy in preventing death from drug intoxication during treatment, but there may be differences between treatments in the specific drugs contributing to death and in the... (Source: SafetyLit)
Source: SafetyLit - December 23, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Chronic opioid treatment may raise risk of post-traumatic stress disorder, study finds
While opioids are often prescribed to treat people with trauma-related pain, a new UCLA-led study suggests doctors should use caution before prescribing the drug to those they believe may experience severe stress in the future, in order to reduce the risk the patient will develop PTSD.In the study, researchers administered doses of the opioid morphine to a group of 22 mice for one week, then gave the mice relatively strong foot shocks. After the morphine wore off, the mice were given mild electric foot shocks. These mice showed a substantially longer “freezing response” than a second, control group of 24 mice t...
Source: UCLA Newsroom: Health Sciences - December 3, 2019 Category: Universities & Medical Training Source Type: news

Seychelles: Drug Rehab Centre to Be Built in Bon Espoir to Tackle Drug Programme, Seychelles' Government Says
[Seychelles News Agency] Tackling the drug problem in Seychelles is a top priority of the government, which views the country's methadone programme as a cost-effective method to deal with the threat, top officials said on Monday. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 3, 2019 Category: African Health Source Type: news

Doctors should avoid co-prescribing benzodiazepines to opioid dependent patients due to increase in overdose death
Doctors should avoid co-prescribing benzodiazepines to opioid dependent patients who are being treated with methadone or buprenorphine, also known as opioid agonist treatment (OAT), due to a three-fold increase in risk of overdose death, according to a study led by researchers at the University of Bristol. (Source: University of Bristol news)
Source: University of Bristol news - November 26, 2019 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Population Health Sciences, Faculty of Health Sciences, Bristol Medical School; Press Release Source Type: news

Cannabis found not to be a substitute for opioids
(McMaster University) The research team looked at all research on the effects of cannabis use on illicit opioid use during methadone maintenance therapy, which is a common treatment for opioid use disorder, and found six studies involving more than 3,600 participants. A meta-analysis of the studies found cannabis use didn't reduce illicit opioid use during treatment nor did it retain people in treatment. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 19, 2019 Category: International Medicine & Public Health Source Type: news

Drug abuse and behavioral transgressions during methadone maintenance treatment (MMT) are related to high psychopathy levels - Potik D, Abramsohn Y, Schreiber S, Adelson M, Peles E.
Introduction: Studies which used the Psychopathy Checklist-Revised (PCL-R) among methadone maintenance treatment (MMT) patients focused mostly on methodological issues, without addressing its relationship to patients' misconduct during treatment. Th... (Source: SafetyLit)
Source: SafetyLit - November 16, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Willingness to take buprenorphine/naloxone among people who use opioids in Vancouver, Canada - Weicker SA, Hayashi K, Grant C, Milloy MJ, Wood E, Kerr T.
OBJECTIVES: Opioid agonist therapy is the cornerstone of treatment of opioid use disorder. In Canada, buprenorphine/naloxone has recently been adopted as the first line agonist therapy given its comparable effectiveness to methadone and superior safety pro... (Source: SafetyLit)
Source: SafetyLit - November 16, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Chautauqua hospital funded for 100-slot addictions program
A Jamestown hospital will expand its addiction program with an additional 100 slots for outpatient treatment. UPMC Chautauqua received new funding from the state Office of Addiction Services and Supports to establish a new opioid treatment program (OTP), the first such program in Chautauqua County. The nearest providers of methadone maintenance are 50 to 70 miles away in Buffalo or Erie, Pennsylvania, all of which have waiting lists. The program, to be located at its Jones Memorial Health Center… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 12, 2019 Category: Pharmaceuticals Authors: Tracey Drury Source Type: news

Evaluation of the effectiveness of auricular acupuncture in suicidal ideation and cortisol level in dysthymic patients with comorbid opiate use disorders enrolled in methadone maintenance treatment: a randomized, double-blind, sham-controlled trial - Pirnia B, Mohammadi AR, Zahiroddin A, Bazargan NM, Malekanmehr P, Pirnia K.
Suicide is one of the leading causes of death around the world. The hypothalamic-pituitary-adrenal (HPA) axis disorder is involved in the pathophysiology of suicidal behavior. Acupuncture by regulating the activity of the HPA axis could regulate the secret... (Source: SafetyLit)
Source: SafetyLit - November 2, 2019 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news

Meditation makes drugs for treating opioid addiction 1.5 times more effective
A new study from Rutgers University in New Jersey, found those recovering from opioid addiction were better at controlling cravings if they practiced mindfulness along with using methadone. (Source: the Mail online | Health)
Source: the Mail online | Health - October 18, 2019 Category: Consumer Health News Source Type: news

Former Roswell Park Nurse Charged with Stealing Pain Meds and Violating HIPAA
Kelsey A. Mulvey, Grand Island NY, fraud, tampering, Roswell Park Comprehensive Cancer Center, hydromorphone, Dilaudid, methadone, oxycodone, lorazepam, Pyxis, water, waterborne infections, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - October 7, 2019 Category: Medical Law Authors: DOJ Source Type: news

Barrier to rural opioid treatment: driving distance to methadone clinics
New research finds that some rural patients have to drive as long as two hours to access methadone treatment, which could be mitigated by new regulations. (Source: Yale Science and Health News)
Source: Yale Science and Health News - October 1, 2019 Category: Universities & Medical Training Source Type: news

For Rural Patients, Opioid Treatment Centers Often Too Far Away
TUESDAY, Oct. 1, 2019 -- Methadone is often used in the fight against opioid addiction, but long travel times in rural areas may be hampering efforts to get more people treated, a new study finds. If methadone for opioid addiction was available in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 1, 2019 Category: General Medicine Source Type: news

Methadone-induced toxic encephalopathy in pediatric patients: two case reports - Tiong SC, Chieng JSL, Khoo HW, Ng CH.
Toxic encephalopathy is a wide spectrum of encephalopathy secondary to insult from toxic substances, with variable clinical presentations from minor cognitive impairment to severe neurological dysfunction and death. Methadone-induced toxic encephalopathy i... (Source: SafetyLit)
Source: SafetyLit - September 30, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Pharmaceutical Treatments for Opioid Abuse May Benefit Teens
TUESDAY, Sept. 17, 2019 -- Teens who misuse prescription or illicit opioids might benefit from the opioid treatment medications methadone, buprenorphine, and naltrexone, according to a review published online Sept. 10 in the Journal of Studies on... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 17, 2019 Category: Pharmaceuticals Source Type: news

Opioid treatment for teens? Medications can help
Methadone, buprenorphine, or naltrexone — already common treatments for opioid use disorders in adults — may also be helpful for teens battling addiction. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 11, 2019 Category: Universities & Medical Training Source Type: news

methadone (Dolophine, Methadose)
Title: methadone (Dolophine, Methadose)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 8/19/2019 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - August 19, 2019 Category: Anesthesiology Source Type: news

Methadone treatment during pregnancy doesn't hurt newborn, study suggests
Treating a pregnant woman who suffers from opioid addiction has no more harmful impact on the newborn compared to receiving no treatment at all, a new study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 15, 2019 Category: Consumer Health News Source Type: news

Abbott Targets Drug and Alcohol-Impaired Drivers in New Collaboration
Abbott Laboratories has developed a portable tool to help law enforcement agencies crack down on people driving under the influence. The Abbott Park, IL-based company looks to expand the reach of the diagnostic tool – SoToxa Mobile Test System- through a marketing agreement with Intoximeters. SoToxa is an oral fluid roadside testing solution that rapidly detects recent drug use. The device tests for marijuana, cocaine, opiates, methadone, amphetamine, and benzodiazepines. Abbott inherited the device when it acquired Alere in 2017 for $5.3 billion. Under the agreement, St. Louis, MO-based Intoximeters will...
Source: MDDI - August 14, 2019 Category: Medical Devices Authors: Omar Ford Tags: IVD Source Type: news

Mindfulness-Oriented Recovery Enhancement (MORE) May Reduce Opioid Cravings and Chronic Pain
Study results suggest mindfulness-oriented recovery enhancement (MORE) may be a useful nondrug complementary treatment for people with opioid use disorder and chronic pain in methadone maintenance therapy. (Source: NCCAM Featured Content)
Source: NCCAM Featured Content - August 9, 2019 Category: Complementary Medicine Authors: NCCIH Source Type: news