U.S. clinics slower to provide opioid treatment than Canadian clinics
Yale researchers found that, during the pandemic, those seeking methadone treatment in the U.S. had to wait nearly twice as long for care. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 23, 2021 Category: Universities & Medical Training Source Type: news

US clinics slower to provide opioid treatment than Canadian clinics
(Yale University) As opioid overdose deaths rose during the COVID-19 pandemic, people seeking treatment for opioid addiction had to wait nearly twice as long to begin methadone treatment in the United States than in Canada, a new Yale study has shown. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 23, 2021 Category: International Medicine & Public Health Source Type: news

Pandemic-based approach to methadone treatment restrictions should remain
A YSPH study finds concerns about lapses in care unfounded concerning relaxed federal regulations for dispensing the common opioid use treatment. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 20, 2021 Category: Universities & Medical Training Source Type: news

Psychometric performance of the perceived stigma of substance abuse scale (PSAS) among patients on methadone maintenance therapy in Vietnam - Stockton MA, Mughal AY, Bui Q, Greene MC, Pence BW, Go V, Gaynes BN.
BACKGROUND: People who inject drugs (PWID) and patients on methadone maintenance therapy (MMT) face severe stigma and discrimination. However, there are limited measures assessing stigma towards individuals with substance use disorders or MMT patients, par... (Source: SafetyLit)
Source: SafetyLit - July 8, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Methadone toxicity in a pediatric patient: a case report - Lumba P, Medows M, Lumba H, Bray L.
In this report, we discuss a case of  a four-year-old boy who presented with respiratory distress and a depressed level of consciousness. A urine drug t... (Source: SafetyLit)
Source: SafetyLit - June 14, 2021 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

The abuse characteristics of amphetamine-type stimulants in patients receiving methadone maintenance treatment and buprenorphine maintenance treatment - Liu Y, Liu N, Shen W, Li L, Zhou W, Xu L.
OBJECTIVE: The purpose of this study was to retrospectively investigate the abuse characteristics of amphetamine-type stimulants (ATS) in patients receiving methadone maintenance treatment (MMT) and buprenorphine maintenance treatment (BMT). METHOD... (Source: SafetyLit)
Source: SafetyLit - May 31, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Medication Treatment of Opioid Use Disorder Can Protect Against Overdose Death
Fewer overdose deaths occurred among adults treated with opioid agonist medications than among those not treated with medication. (Source: NIDA News)
Source: NIDA News - May 21, 2021 Category: Addiction Tags: Buprenorphine, Methadone, NIDA Notes, Opioids, Treatment Research, Treatment Source Type: news

Methadone and Ketamine for Postop Pain in Spinal Surgery Methadone and Ketamine for Postop Pain in Spinal Surgery
Might a combination of ketamine and methadone given postoperatively reduce the need for opiates in patients recovering from spinal surgery?Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 18, 2021 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Long-lasting medications may improve treatment satisfaction in people with opioid use disorder
NIH leaders emphasize the importance of patient voices in addiction medication development (Source: NIDA News)
Source: NIDA News - May 10, 2021 Category: Addiction Tags: Buprenorphine, News Release, Fentanyl, Health and Medical Professionals, Illicit Opioids, Medication Development, Methadone, NIDAMED News, Opioids, Researchers, Addiction Science Source Type: news

Mortality in an opioid treatment program - Bhatraju EP, Fuller C, Grekin P, Rockman S, Peavy KM.
This retrospective study examined mortality in an Opioid Treatment Program (OTP) with policies designed to admit and retain patients with as few barriers as possible. Methadone provided in the context of an OTP is known to decrease mortality and morbidity.... (Source: SafetyLit)
Source: SafetyLit - April 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Evidence for the transfer of methadone and EDDP by sweat to children's hair - Feld K, Dahm P, Kieliba T, Klee A, Rothschild MA, Andresen-Streichert H, Beike J.
In cases where there is a question as to whether children have come into contact with drugs, examinations of their scalp hair are frequently carried out. Positive test results are often discussed in the forensic community due to the various possible modes ... (Source: SafetyLit)
Source: SafetyLit - April 8, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Inside Ibogaine, One of the Most Promising and Perilous Psychedelics for Addiction
Amber Capone had become afraid of her husband. The “laid-back, bigger than life and cooler than cool” man she’d married had become isolated, disconnected and despondent during his 13 years as a U.S. Navy SEAL. Typically, he was gone 300 days of the year, but when he was home, Amber and their two children walked on eggshells around him. “Everyone was just playing nice until he left again,” Amber says. In 2013, Marcus retired from the military. But life as a civilian only made his depression, anger, headaches, anxiety, alcoholism, impulsivity and violent dreams worse. Sometimes he’d get up...
Source: TIME: Health - April 5, 2021 Category: Consumer Health News Authors: Mandy Oaklander Tags: Uncategorized Drugs feature Magazine Mental Health Source Type: news

Mary Jeanne Kreek, Methadone Developer, Dies at 84
A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction. (Source: The Scientist)
Source: The Scientist - March 31, 2021 Category: Science Tags: News & Opinion Source Type: news

Forensic pathological study of methadone-related deaths in the Genoa (Italy) district: a six-year study - Errico S, Bedocchi D, Drommi M, Barranco R, Bonsignore A, Ventura F.
Methadone is a synthetic opioid, a pure agonist of the μ receptor. It is used for opioid maintenance therapy in heroin addiction. In recent years, Italian studies of incidence and prevalence have indicated an increase in the illegal sales of methadone and... (Source: SafetyLit)
Source: SafetyLit - March 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Opioid agonist treatment could substantially reduce drug related deaths if used more widely
New evidence that opioid agonists such as methadone and buprenorphine could substantially reduce drug related deaths if more widely used in the community and prison, and for longer, has been published in Lancet Psychiatry today [25 February]. (Source: University of Bristol news)
Source: University of Bristol news - February 25, 2021 Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Health Sciences, Faculty of Health Sciences, Population Health Sciences; Press Release Source Type: news

Trends and geographic patterns in drug and synthetic opioid overdose deaths - United States, 2013-2019 - Mattson CL, Tanz LJ, Quinn K, Kariisa M, Patel P, Davis NL.
Deaths involving synthetic opioids other than methadone (synthetic opioids), which largely consist of illicitly manufactured fentanyl; psychostimulants with abuse potential (e.g., methamphetamine); and cocaine have increased in recent years, particularly s... (Source: SafetyLit)
Source: SafetyLit - February 15, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Mexico ’s poor have little luck obtaining opioids intended for palliative care
If you ’re poor and terminally ill in southern Mexico, there’s far less chance you’ll get the painkillers you need for palliative care than your cousins in more prosperous regions, particularly those pharmacy-rich areas along Mexico–U.S. border, say UCLA researchers and colleagues who studied opioi d dispensing levels across the country.What ’s more, the researchers’ paper in the journalThe Lancet Public Health suggests it ’s likely that some of the opioids intended for Mexican citizens are ending up in American pockets.Despite a Mexican government initiative launched in 2015 to im...
Source: UCLA Newsroom: Health Sciences - February 11, 2021 Category: Universities & Medical Training Source Type: news

Cannabis Dispensaries Negatively Linked to Opioid - Related Death
Particularly strong negative association seen for dispensary count with deaths caused by synthetic opioids other than methadone (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - February 6, 2021 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Emergency Medicine, Pharmacy, Psychiatry, Anesthesiology & amp; Pain, Journal, Source Type: news

Prevalence of amphetamine-type stimulant use and related factors among methadone maintenance patients in Ho Chi Minh City Vietnam: a cross-sectional study - Le NT, Khuong QL, Vu TTV, Thai TT, Le HTCH, Dao PT, Le SH, Tieu TTV, Do VD.
The objective of this study was to determine the prevalence of amphetamine-type stimulant use and associated factors among methadone maintenance treatment (MMT) patients. In 2018, a cross-sectional study was conducted on 967 MMT patients at two methadone c... (Source: SafetyLit)
Source: SafetyLit - February 1, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Unintentional buprenorphine and methadone poisoning in children: a matched observational study - Farnaghi F, Gholami N, Hassanian-Moghaddam H, McDonald R, Zamanzadeh R, Zamani N.
OBJECTIVE: To compare accidental pediatric poisoning from methadone vs. buprenorphine in terms of clinical indicators and in-hospital morbidity. METHODS: A matched observational study conducted on children aged ≤12 years admitted to our center ... (Source: SafetyLit)
Source: SafetyLit - January 25, 2021 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Continuity of illicit drug use among Malay patients attending methadone clinics in Kelantan, Malaysia - Ab Lloh S, Mohamad N, Badrin S, Abu Bakar R, Ahmad I.
The study aimed to determine the prevalence of continuity of illicit drug use and its associated factors among Malay opioid users receiving methadone treatment in Kelantan, Malaysia. This cross-sectional study involved a total of 150 respondents. Sociodemo... (Source: SafetyLit)
Source: SafetyLit - January 25, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

How Long Do You Monitor Neonates for Neonatal Abstinence Syndrome (NAS)?
Discussion Neonatal abstinence syndrome (NAS) occurs in the first few days of life and is a complex withdrawal syndrome. The newborn is abruptly cut-off from their exposure to licit or illicit drugs that the mother is chronically consuming and which were being transmitted through the placenta to the fetus. “NAS is a highly variable and severe condition; it may be associated with central and autonomic nervous system dysfunction … and gastrointestinal disorders.” It can cause significant morbidity but is rarely fatal. Fetal exposure has been increasing in the United States. In 2011-12, almost 5.9% of pregn...
Source: PediatricEducation.org - January 11, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

FDA Drug Safety Communication: FDA urges caution about withholding opioid addiction medications from patients taking benzodiazepines or CNS depressants: careful medication management can reduce risks
Based on our additional review, the U.S. Food and Drug Administration (FDA) is advising that the opioid addiction medications buprenorphine and methadone should not be withheld from patients taking benzodiazepines or other drugs that depress the central nervous system (CNS). The combined use of these drugs increases the risk of serious side effects; however, the harm caused by untreated opioid addiction usually outweighs these risks. Careful medication management by health care professionals can reduce these risks. We are requiring this information to be added to the buprenorphine and methadone drug labels along with detai...
Source: FDA Center for Drug Evaluation and Research - What's New - January 7, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children - Gholami N, Farnaghi F, Saberi M, Zamani N, McDonald R, Hassanian-Moghaddam H.
BACKGROUND: The prevalence of poisoning from methadone and prescription opioids is increasing in pediatric populations. Naloxone is the main antidote for treatment. Long-acting opioid toxicity may need close observation in the intensive care unit (ICU). In... (Source: SafetyLit)
Source: SafetyLit - December 10, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Massachusetts Contact Tracing Program Hiring As Coronavirus Cases Rise
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 28, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Syndicated CBSN Boston Syndicated Local Coronavirus Source Type: news

NH Soccer Teams Forfeit Tournament Games When Oppenents Decline To Wear Masks
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 28, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Covid-19 Boston, MA Health News schools Syndicated CBSN Boston Syndicated Local Beth Germano Newmarket NH Source Type: news

Baker: Families Should ‘ Think Long And Hard ’ About Holiday Plans And Skip Gatherings
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 27, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Syndicated CBSN Boston Syndicated Local Coronavirus Gov. Charlie Baker Source Type: news

Baker Warns Of ‘ Significant Increase ’ In Coronavirus Cases Among Younger People
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 27, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Syndicated CBSN Boston Syndicated Local Coronavirus Source Type: news

UPMC Chautauqua withdraws plans for methadone program
After four years of planning, the hospital says there are enough services by other providers and partnerships have improved. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 22, 2020 Category: American Health Authors: Tracey Drury Source Type: news

Methadone (Methadone Oral Concentrate) - updated on RxList
Methadone Oral Concentrate may treat opioid addiction, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. (Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 22, 2020 Category: Drugs & Pharmacology Source Type: news

"That's no longer tolerated": policing patients' use of non-opioid substances in methadone maintenance treatment - Frank D.
The current overdose crisis in the United States emphasizes the importance of providing substance use treatment programs that are not only effective but tailored to meet the specific needs of the populations they serve. While Methadone Maintenance Treatmen... (Source: SafetyLit)
Source: SafetyLit - October 2, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The relationship between mindfulness and borderline personality and suicidal thoughts in people under methadone maintenance therapy in Rafsanjan in 2018: a descriptive study - Sadeghi M, Mirzaeirad R.
In this study, the relationship between mindfulness and ... (Source: SafetyLit)
Source: SafetyLit - September 28, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Suicide attempts and death among heroin-involved women seeking methadone treatment in Taiwan - Chen WT, Wang SC, Wang IA, Tsay JH, Chen CY.
BACKGROUND: The present study aims to profile the hazard fluctuation of suicide attempts and deaths among heroin-involved women seeking methadone maintenance treatment (MMT) and to investigate sociodemographic and clinical factors predicting the time to ha... (Source: SafetyLit)
Source: SafetyLit - September 26, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Clinical characteristics and time trends of hospitalized methadone exposures in the United States based on the Toxicology Investigators Consortium (ToxIC) case registry: 2010-2017 - Mehrpour O, Hoyte C, Amirabadizadeh A, Brent J, Toxicology Investigators Consortium (ToxIC).
BACKGROUND: Methadone is well known for its long duration of action and propensity for mortality after an overdose. The present research was aimed at evaluating the clinical manifestations and time trends of methadone exposure in patients in US hospitals. ... (Source: SafetyLit)
Source: SafetyLit - July 27, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Travel Times to Opioid Addiction Programs Drive a Lack of Access Travel Times to Opioid Addiction Programs Drive a Lack of Access
Allowing pharmacies in the US to dispense methadone would significantly reduce the time involved in obtaining the medication and save money, new research shows.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - July 20, 2020 Category: Internal Medicine Tags: Psychiatry News Source Type: news

Patients with substance use disorder discriminated against by post-acute care facilities
(Boston Medical Center) A new study shows that 29 percent of private post-acute care facilities in Massachusetts explicitly discriminated against hospitalized individuals with opioid use disorder, rejecting their referral for admission. Led by researchers at Boston Medical Center's (BMC's) Grayken Center for Addiction, the study showed that 15 percent of the rejections among patients with substance use disorders were denied due to a substance use disorder diagnosis or because they were being treated for opioid use disorder with buprenorphine or methadone. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 16, 2020 Category: Infectious Diseases Source Type: news

Under 2% of Medicaid-covered youths get MAT after OD: study - Knopf A.
Fewer than one-third of youths receive addiction treatment after an opioid overdose, and only one in 54 receive pharmacotherapy (methadone, buprenorphine or naltrexone), a study published in JAMA Pediatrics reports. The researchers urge interventions to li... (Source: SafetyLit)
Source: SafetyLit - July 14, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Kenya: Recovering Drug Addicts in Kenya Find Treatment Difficult With COVID-19
[RFI] Covid-19 regulations in Kenya pose additional challenges to recovering drug addicts along the coastal areas, who say they are finding it difficult to access their methadone recovery programs due to an inter-county lockdown and dusk to dawn curfew. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 6, 2020 Category: African Health Source Type: news

Methadone-related deaths among youth and young adults in Sweden 2006-2015 - Fugelstad A, Bremberg S, Hjelmstr öm P, Thiblin I.
AIMS: To identify methadone-related deaths and determine the prevalence among youth and young adults in Sweden 2006-2015. DESIGN, SETTING AND PARTICIPANTS: National retrospective registry study comparing data from all forensic autopsy examinations and ... (Source: SafetyLit)
Source: SafetyLit - June 17, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Meds2Go Express Pharmacy, Inc. Sentenced for Role in Drug Diversion Scheme
FDA OCI, Alum Creek WV, Meds2Go Express Pharmacy, drug diversion, sentencing, money laundering, conspiracy, Hope Clinic, pain clinic, pill mill, opioids, oxycodone, methadone, addicts, illegal manufacturing, restitution, forfeiture, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - June 3, 2020 Category: Medical Law Authors: DOJ Source Type: news

Relationship between Buddhist belief and suicide risk in Chinese persons undergoing methadone maintenance therapy for heroin dependence - Huang JX, Xu YM, Zhong BL.
BACKGROUND: In western countries, there is a negative association between religious belief and suicide risk, while in China this association is positive. Nevertheless, few data are available on the association between one specific type of religion and suic... (Source: SafetyLit)
Source: SafetyLit - June 3, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

US relaxes rules for opioid substitutes during lockdowns
Trump administration makes it easier for addicts to obtain methadone and other treatment drugs (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - May 28, 2020 Category: Pharmaceuticals Source Type: news

One-third of primary care physicians do not support the use of medications for treating opioid use disorders
(American College of Physicians) A survey of primary care physicians found that one-third did not perceive medications to treat OUD to be more effective than nonmedication treatment or safe for long-term use, despite conclusive evidence to the contrary. Physicians also reported low interest in treating OUD and low support for policy proposals allowing office-based physicians to prescribe buprenorphine and methadone. These findings are reported in a brief research report published in Annals of Internal Medicine. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 20, 2020 Category: International Medicine & Public Health Source Type: news

Coronavirus: Recovering heroin addicts offered monthly injections
Daily trips to the pharmacy for methadone are replaced with monthly buprenorphine injections. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - April 18, 2020 Category: Consumer Health News Source Type: news

Impact of pharmacological treatments for opioid use disorder on mortality - Kelty E, Hulse G, Joyce D, Preen DB.
The use of pharmacological treatments for opioid use disorders, including methadone, buprenorphine and naltrexone has been associated with a reduction in mortality compared with illicit opioid use. However, these treatments can also contribute significantl... (Source: SafetyLit)
Source: SafetyLit - March 31, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Flawed studies distort risk of opioid addiction treatment while pregnant
Studies that assess risks to pregnant women undergoing treatment for opioid addiction may have significant flaws that overstate the impact of drugs like buprenorphine and methadone on child development. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 19, 2020 Category: Consumer Health News Source Type: news

Drug and Opioid-Involved Overdose Deaths - United States, 2017-2018
From 2017 to 2018, U.S. overdose death rates involving synthetic opioids (excluding methadone) increased by 10%, death rates involving heroin decreased by 4%, and prescription opioid-involved overdose death rates decreased by 13.5%. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - March 19, 2020 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Overdose Prescription Drug Abuse Synthetic Opioids Source Type: news

FAQs: Provision of Methadone and Buprenorphine for the Treatment of Opioid Use Disorder in the COVID-19 Emergency
Source: Substance Abuse and Mental Health Services Administration (SAMHSA). Published: 3/19/2020. This two-page document provides answers to frequently asked questions about providing methadone and buprenorphine for the treatment of opioid use disorder during the COVID-19 (coronavirus) epidemic. Topics include the use of telehealth for new and existing patients, and dispensing medication based on telehealth. (PDF) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - March 19, 2020 Category: International Medicine & Public Health Source Type: news

6 Italian inmates die during protest over virus measures
They died after breaking into the infirmary and overdosing on methadone. (Source: ABC News: Health)
Source: ABC News: Health - March 9, 2020 Category: Consumer Health News Tags: Health Source Type: news