Neuroanatomical markers of familial risk in adolescents with conduct disorder and their unaffected relatives

CONCLUSIONS: These findings suggest that alterations in inferior parietal cortical structure partly mediate the effects of familial risk for CD. These structural changes merit investigation as candidate endophenotypes for CD. Neuroanatomical changes in medial orbitofrontal and anterior cingulate cortex differentiated between URs and the other groups, potentially reflecting neural mechanisms of resilience to CD.PMID:34607618 | DOI:10.1017/S0033291721003202

Source: Psychological Medicine - October 5, 2021 Category: Psychiatry Authors: Graeme Fairchild Kate Sully Luca Passamonti Marlene Staginnus Angela Darekar Edmund J S Sonuga-Barke Nicola Toschi Source Type: research