Effect of hepatitis C eradication with DAA on type II diabetes mellitus control as regard insulin resistance & amp; lipid profile

ConclusionThe overall data of this study show that glycemic control improves in patients with diabetes after DAA induced SVR. Patients not only have an improvement in HbA1c level after achieving SVR, they are also less likely to require insulin. the viral clearance due to DAA also led to an improvement of glucose metabolism associated with a global worsening of lipid profile. The HCV clearance by DAA treatment reverses or improves IR and reduces stress on beta-cell function by emphasizing the role of HCV in the development of IR and that this result can prevent IR-related pathological conditions such as worsening liver fibrosis, development of type 2 diabetes, metabolic syndrome and cardio-vascular disorders.
Source: QJM - Category: Internal Medicine Source Type: research