Study of Retinal and Choroidal Changes in Children with Sickle Cell Disease using Optical Coherence Tomography and Angiography

ConclusionSD-OCT and OCTA were able to detect areas of thinning and decreased vascular densities in asymptomatic sickle cell children. This study demonstrated a decreased vessel density on OCTA but a normal retinal thickness on SD-OCT in some of the parafoveal sucfields. This suggests that OCTA can detect microvascular abnormalities and retinopathy early even before it is visible on OCT. Further longitudinal studies are needed to examine the vascular densities and retinal and choroidal thinning in sickle cell disease children and their correlation with the various disease parameters.
Source: QJM - Category: Internal Medicine Source Type: research