Glucocorticoids for therapeutic immunosuppression: Clinical pearls for the practicing neurologist
Given widespread use of glucocorticoid therapy in neurologic disease, understanding glucocorticoid pharmacology and risk is paramount for the practicing neurologist. While dosing and tapering regimens vary depending on the neurological disease and indication being treated, there are important general principles of glucocorticoid prescribing and monitoring that can guide clinical decision-making. Glucocorticoid-related toxicities can occur across multiple organ systems, including hypertension; dyslipidemia; weight gain; hyperglycemia; osteoporosis and avascular necrosis; myopathy; gastrointestinal bleeding; infection; and neuropsychiatric effects with sleep, mood disturbance and cognition.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Alexandra Galati, E. Sherwood Brown, Riley Bove, Anand Vaidya, Jeffrey Gelfand Tags: Review Article Source Type: research
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