Tubulointerstitial nephritis and uveitis syndrome following meningitis and systemic lymphadenopathy with persistent Toxoplasma immunoglobulin M: a case report

ConclusionsWe experienced a case of diclofenac-induced tubulointerstitial nephritis and uveitis syndrome. In ruling out infections,Toxoplasma immunoglobulin M was persistently positive, andToxoplasma immunoglobulin G avidity test indicated a “distant” infection. From these two results, we ruled out recent infection. However, it should be noted that “distant” infection indicated by commercial immunoglobulin G avidity is still a multiplex profile consisting of reinfection, reactivation, and latent infection. Narrowing down the inf ection profile ofToxoplasma is challenging in some cases. Therefore, careful diagnosis and extended follow-up of such patients are needed.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research