Review of the Preanalytical Errors That Impact Therapeutic Drug Monitoring

Conclusions: The identification of preanalytical factors that may negatively impact TDM is critical. Developing workflows that can standardize TDM practices, align appropriate timing and blood collection techniques, and specimen processing will eliminate errors.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Review Article Source Type: research

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This study highlights the findings of a novel multimodal ERAS protocol employed by two surgeons at a single institution performing mastectomy with immediate implant-based reconstruction and the data extrapolated demonstrates how it may influence narcotic use and length of stay in the hospital.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Breast Source Type: research
To test the hypothesis that the use of single drain results in similar morbidity with significantly less pain as in double drain in patients undergoing modified radical mastectomy (MRM).
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Breast Source Type: research
Small intestinal bacterial overgrowth (SIBO) is a common problem after bariatric surgery leading to abdominal pain, bloating, and diarrhea. However, little data exists on the prevalence or presenting symptoms of SIBO after BS. We sought to define the prevalence, risk factors, and outcomes of SIBO in a bariatric population by performing a retrospective cohort study.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Bariatric and Foregut Source Type: research
Bariatric patients are at increased risk of opioid use disorder. There is a national effort to reduce opioid use after bariatric surgery. We instituted a standardized multimodal pain regimen to address this need.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: Bariatric and Foregut Source Type: research
Over 5 million Americans currently abuse prescription opioids. We standardized postoperative opioid prescribing habits amongst surgical providers at our institution, and then analyzed patients ’ postoperative pain control habits.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: General Surgery Source Type: research
Chronic groin pain (CGP), defined as pain beyond two months, is a rare but potentially debilitating complication of inguinal hernia repair. CGP etiologies include neuropathic, mesh-related, hernia-related, musculoskeletal, and urologic. Treatment options depend on the nature of the pain. Preoperative history, physical exam and imaging studies can help elucidate the cause, while surgical exploration and interventions are sometimes required. The purpose of this study was to evaluate the outcomes following CGP surgical treatment.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: General Surgery Source Type: research
Lichtenstein ’s Repair is an easy technique to master during residency, with reproducible results. However, the onset of Mesh repairs masks a sinister complication, Inguniodynia, or Iatrogenic Denervations that is quite common with Residents. Álvarez et al developed a Dermatome Mapping technique. This was lat er modified into the Dermatome mapping classification (DMC).
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: General Surgery Source Type: research
Control of acute pain and reduction of opioid use is important in the postoperative phase of patient care. “Cryotherapy” refers to the use of low temperatures for therapeutic purposes. Our objective was to systematically review and meta-analyze whether the application of cryotherapy on closed incisions reduces postoperative pain and opioid consumption.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: General Surgery Source Type: research
This study aimed to identify the impact of round ligament division (RLD) or preservation (RLP) on short and medium-term quality of life.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: General Surgery Source Type: research
Though it is well established that musculoskeletal injuries are common among surgeons, most prior research has focused on risk associated with various surgical specialties, rather than with various operative techniques. We sought to determine the epidemiology and associated burden of musculoskeletal injuries and pain at our institution and hypothesized that injuries and pain would be more common with certain operative techniques than others.
Source: Journal of the American College of Surgeons - Category: Surgery Authors: Tags: General Surgery Source Type: research
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