Recurrent gastrointestinal bleeding due to vascular malformations in a girl with Turner syndrome

We present a description of a 12-year-old patient with TS and vascular malformations in the GI tract who was admitted to the hospital because of recurrent microcytic anemia. At the age of 15, she started estrogen therapy due to hypogonadism. Since then, the bleeding has stopped and the number of malformations on follow-up colonoscopy has been significantly decreased. In TS patients with iron deficiency anemia, the differential diagnostics should include vascular defects in the GI. There are evidences, that estrogen therapy may limit the number of lesions and reduce the risk of bleeding.PMID:34431260 | DOI:10.5114/pedm.2021.105636
Source: Pediatric Endocrinology, Diabetes, and Metabolism - Category: Endocrinology Authors: Source Type: research