Acute kidney injury in critically Ill children and young adults with suspected SARS-CoV2 infection

CONCLUSIONS: AKI and severe AKI occur commonly in critically ill children with SARS-CoV2 infection, more than double the historical standard. Further investigation is needed during this continuing pandemic to describe and refine the understanding of pediatric AKI epidemiology and outcomes.TRIAL REGISTRATION: NCT01987921.IMPACT: What is the key message of the article? AKI occurs in children exposed to the novel SARS-CoV2 virus at high prevalence (~40% with some form of AKI and 20% with severe AKI). What does it add to the existing literature? Acute kidney injury (AKI) occurs commonly in adult patients with SARS-CoV2 (COVID), very little data describes the epidemiology of AKI in children exposed to the virus. What is the impact? A pediatric vaccine is not available; thus, the pandemic is not over for children. Pediatricians will need to manage significant end-organ ramifications of the novel SARS-CoV2 virus including AKI.PMID:34331019 | DOI:10.1038/s41390-021-01667-4

Source: Pediatric Research - July 31, 2021 Category: Pediatrics Authors: Rajit K Basu Erica C Bjornstad Katja M Gist Michelle Starr Paras Khandhar Rahul Chanchlani Kelli A Krallman Michael Zappitelli David Askenazi Stuart L Goldstein SPARC Investigators Source Type: research