Synthesis and biological activity of novel 4-aminoquinoline/1,2,3-triazole hybrids against Leishmania amazonensis

In conclusion, data suggest that derivative 4 presents selective antileishmanial effect, which is associated with multi-target action, and can be considered for future studies for the treatment against disease.PMID:34323702 | DOI:10.1016/j.biopha.2021.111857

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 29, 2021 Category: Drugs & Pharmacology Authors: N ícolas Glanzmann Luciana Maria Ribeiro Antinarelli Isabelle Karine da Costa Nunes Henrique Marcelo Gualberto Pereira Eduardo Antonio Ferraz Coelho Elaine Soares Coimbra Adilson David da Silva Source Type: research