Direct thrombectomy versus bridging thrombolysis with mechanical thrombectomy in middle cerebral artery stroke: a real-world analysis through National Inpatient Sample data

CONCLUSIONS: In the analysis of the NIS database, the MT+IVT group had significantly higher rates of minimal disability at the time of hospital discharge versus the MT-alone group, despite a higher rate of ICH. The question of whether to treat patients with MT+IVT rather than MT alone is currently being addressed in ongoing prospective clinical trials (SWIFT-DIRECT [NCT03494920], MR CLEAN-NO IV [ISRCTN80619088], and DIRECT-SAFE [NCT03494920]). The results of these studies will contribute to greater understanding and progressive improvement in outcomes for AIS patients.PMID:34198246 | DOI:10.3171/2021.4.FOCUS21132

Source: Neurosurgical Focus - July 1, 2021 Category: Neurosurgery Authors: Sandeep Kandregula Amey R Savardekar Pankaj Sharma Jerry McLarty Jennifer Kosty Krystle Trosclair Hugo Cuellar Bharat Guthikonda Source Type: research