Using mice to open the way to prevent blocked arteries

(Tokyo Medical and Dental University) Researchers from Tokyo Medical and Dental University (TMDU) have identified important parts of the pathway by which a high-fat diet affects the body's immune response, leading eventually to atherosclerosis. Working with mouse models, they clarified how histone H3 citrullination activates neutrophils with serum CXCL1 elevation. Identifying these steps could lead to new diagnostic tools and treatments for cardiovascular disease.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news