The Effect of Neprilysin Inhibition on Left Ventricular Remodeling in Patients with Asymptomatic Left Ventricular Systolic Dysfunction Late After Myocardial Infarction

Conclusions: In patients with asymptomatic LVSD following MI, treatment with sacubitril/valsartan did not have a significant reverse remodeling effect compared with valsartan. Clinical Trial Registration: URL: https://www.clinicaltrials.gov Unique identifier: NCT03552575.PMID:33983794 | DOI:10.1161/CIRCULATIONAHA.121.054892

Source: Circulation - May 13, 2021 Category: Cardiology Authors: Kieran F Docherty Ross T Campbell Katriona J M Brooksbank John G Dreisbach Paul Forsyth Rosemary L Godeseth Tracey Hopkins Alice M Jackson Matthew M Y Lee Alex McConnachie Giles Roditi Iain B Squire Bethany Stanley Paul Welsh Pardeep S Jhund Mark C Petrie Source Type: research