Relationship Between Central Artery Stiffness, Brain Arterial Dilation, and White Matter Hyperintensities in Older Adults: The ARIC Study

CONCLUSIONS: In this examination of older adults from the general population, larger, plaque-free arterial diameters in the middle cerebral circulation were associated with greater WMH volume, particularly among participants with elevated central artery stiffness. Strategies to reduce central artery stiffness may mitigate the association between cerebrovascular outward remodeling and microvascular damage.PMID:33882687 | DOI:10.1161/ATVBAHA.120.315692

Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 22, 2021 Category: Cardiology Authors: Melissa C Caughey Ye Qiao Michelle L Meyer Priya Palta Kunihiro Matsushita Hirofumi Tanaka Bruce A Wasserman Gerardo Heiss Source Type: research