Placentitis and abortion caused by a multidrug resistant strain of Campylobacter fetus subspecies fetus in a sheep in Uruguay

We describe a case of abortion caused by a multidrug resistant strain of Cff in a sheep in Uruguay. In August 2017, 3/57 pregnant ewes (5.3%) aborted whithin one week. Histopathologic examination of the placenta of an aborted ewe revealed severe neutrophilic and fibrinonecrotizing placentitis with vasculitis and thrombosis of the chorionic arterioles. Cff was isolated on microaerobic culture in Skirrow agar, and further confirmed by 16S rDNA PCR amplification and sequencing, and endpoint and real time PCR assays. Antimicrobial sensitivity testing revealed resistance to tetracyclines, nalidixic acid, telithromycin and clindamycin. Other abortifacients were not detected. Further studies are necessary to determine the geographic distribution, ecology, epidemiology, economic impact, and antimicrobial resistance of Cff in sheep flocks in Uruguay.PMID:33875294 | DOI:10.1016/j.ram.2021.02.005

Source: Revista Argentina de Microbiologia - April 20, 2021 Category: Microbiology Authors: Mat ías A Dorsch Mar ía L Casaux Luc ía Calleros Virginia Ar áoz Rub én D Caffarena Cecilia Monesiglio Maila Barcellos Caroline da Silva Silveira Yisell Perdomo Georgget Banchero Francisco A Uzal Mart ín Fraga Federico Giannitti Source Type: research