Sequential chemotherapy regimen of induction with panitumumab and paclitaxel followed by radiotherapy and panitumumab in patients with locally advanced head and neck cancer unfit for platinum derivatives. The phase II, PANTERA/TTCC-2010-06 study

ConclusionsAlthough underpowered, ORR was higher than the pre-specified boundary for considering the treatment active. Although Px  + Pb as IT provides some benefit, the safety profile is worse than expected. To consider Pb + Px as IT as an alternative for platinum-unsuitable LA-SCCHN, further research/investigation would be needed.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research