Hesperetin modulates the Sirt1/Nrf2 signaling pathway in counteracting myocardial ischemia through suppression of oxidative stress, inflammation, and apoptosis

In conclusion, HSP plays a protective role in ISO-induced myocardial ischemia by modulating oxidative stress, inflammation, and apoptosis via Sirt1/Nrf2 pathway activation.PMID:33839495 | DOI:10.1016/j.biopha.2021.111552

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 11, 2021 Category: Drugs & Pharmacology Authors: Panpan Liu Jinghan Li Miaomiao Liu Muqing Zhang Yucong Xue Yuanyuan Zhang Xue Han Xuan Jing Li Chu Source Type: research