Characterization and functional analysis of the proteins Prohibitin 1 and 2 in < i > Trypanosoma cruzi < /i >

Conclusion/significanceThis research expands our understanding of the functions of PHBs in the life cycle of the parasite. It also highlights the protective role of prohibitins against ROS and reveals that the absence of PHB2 has a lethal effect on the parasite, a fact that could support the consideration of this protein as a possible target for therapeutic action.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research