Janssen Announces Novel Dengue Antiviral Demonstrates Efficacy in Pre-Clinical Data Published in Nature
BEERSE, BELGIUM, March 15, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) announced today the publication of new data in the journal Nature showing that an early-stage clinical candidate (JNJ-1802) provides strong protection against dengue in non-human primates and mice. The first-in-class antiviral, which was shown to be safe and well tolerated in a Phase 1 first-in-human clinical study, is now progressing into Phase 2 clinical studies for the prevention and treatment of dengue.The new data indicate JNJ-1802 is effective against all four of the dengue serotypes in mouse models and provide...
Source: Johnson and Johnson - March 15, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Next-generation bed nets get major endorsement from World Health Organization
A new tool to fight the world’s deadliest animal—the malaria-carrying mosquito—may soon become more widely available. Yesterday, the World Health Organization (WHO) endorsed using a new kind of bed net treated with insecticides. It combines two chemicals to more effectively kill the mosquitoes that transmit the parasite that causes malaria, a disease that killed an estimated 619,000 people in 2022, most of them young children in sub-Saharan Africa. Insecticide-treated bed nets protect people from malaria in two ways. They prevent mosquitoes from reaching the person sleeping under the net, and they kil...
Source: ScienceNOW - March 15, 2023 Category: Science Source Type: news

Nurses should be able to approve abortions, suggests UK study
Nurses and midwives should be able to approve abortions, a UK study has concluded, in what would be the one of the biggest changes to abortion legislation since 1967. The findings of the Shaping Abortion for Change (SACHA) report, which was led by the London School of Hygiene and Tropical Medicine, has recommended significant changes... Read moreThe post Nurses should be able to approve abortions, suggests UK study appeared first on Nursing in Practice. (Source: Nursing in Practice)
Source: Nursing in Practice - March 8, 2023 Category: Nursing Authors: Wiliam Hunter Tags: Latest news Source Type: news

Keto vs. Vegan: What to Eat if You Want to Save the Planet and Your Health
Debates over the benefits and pitfalls of different diets have been around as long as, well, the diets themselves. Is the ketogenic diet a good way to lose weight, or a carb-free trip to bad health? Are vegetarians missing out on vital vitamins? What, exactly, is the omnivore’s dilemma? Can vegans eat sugar? And do paleo adherents actually know what our ancient ancestors ate? A study published this week in The American Journal of Clinical Nutrition can at least put one diet debate to rest: the climate impact of our choices. Our food system is responsible for a third of global emissions—animal agriculture alone ...
Source: TIME: Science - March 1, 2023 Category: Science Authors: Aryn Baker Tags: Uncategorized climate change Climate Is Everything embargoed study Food & Agriculture health healthscienceclimate Source Type: news

Luis Cuevas obituary
My longtime colleague Luis Cuevas, who has died aged 66 of pancreatic cancer, was an academic who specialised in paediatrics, epidemiology and tropical medicine. For most of his career he did his research and teaching at theLiverpool School of Tropical Medicine (LSTM), which he joined in 1985 after fleeing to the UK from political violence in his native Guatemala. He was still working at the LSTM at his death.Luis ’s work focused mainly on the diagnosis and management of diseases of poverty, and one of his most notable achievements was the development of a same-day diagnosis approach for tuberculosis, which was adopted b...
Source: Guardian Unlimited Science - February 24, 2023 Category: Science Authors: Bertie Squire Tags: Medical research Medicine Guatemala Liverpool Tuberculosis Hospitals World Health Organization Source Type: news

Africa: 8th WHO Technical Taskforce - Defeating Meningitis By 2030 - a Global Road Map
[WHO] The 8th meeting was held from Tuesday 13th - Thursday 15th December 2022, chaired by Professor Brian Greenwood (London School of Hygiene and Tropical Medicine - UK) and Professor Samba Sow (Centre for Vaccine Development - Mali). Some 40 Members and WHO staff discussed global updates, regional and country implementation, operationalizing country support, product development and guidelines, surveillance, the investment case to defeat meningitis, and advocacy activities. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 18, 2023 Category: African Health Source Type: news

Nobel-nominated vaccine expert warns of Covid complacency: ‘We’re still losing too many lives’
Dr Peter Hotez says Joe Biden was wrong to say pandemic is over and warns US risks another deadly coronavirus wave soonJoe Biden was wrong to declare the coronavirus pandemic over in the US, one of the country ’s leading experts on the virus has told the Guardian.Dr Peter Hotez, co-director of the Center for Vaccine Development at Texas Children ’s hospital and dean of the National School of Tropical Medicine at Baylor College of Medicine, said that the US president’sstatement in September, that “the pandemic is over”, was mistaken and a poor message to send to the American public.Continue reading... (Source: Gua...
Source: Guardian Unlimited Science - December 23, 2022 Category: Science Authors: Erum Salam Tags: Coronavirus Infectious diseases Science US news Health policy Source Type: news

Tom Meade obituary
Epidemiologist whose research into the role of blood in heart disease paved the way for new targeted treatmentsTom Meade, who has died aged 86, pioneered the field of cardiovascular epidemiology. His research, spanning five decades, gave medical science a vastly improved understanding of the biology of blood and the circulatory system, opening the door for targeted new heart disease treatments.By the early 1960s, heart disease was the leading cause of death in many countries, with the culprit widely believed to be atheroma (fatty deposits inside the arteries), brought on by high cholesterol and a fatty diet. But in 1965, M...
Source: Guardian Unlimited Science - November 22, 2022 Category: Science Authors: Penny Warren Tags: Medical research People in science Heart disease Heart attack London School of Hygiene & Tropical Medicine Source Type: news

Cold Weather Can Be Dangerous for the Human Body. This Winter Worries Experts
A particularly nasty trifecta of influenza, COVID-19, and respiratory syncytial virus (RSV) is already portending a rough winter. But there’s another factor contributing to a potentially tough season for health: a colder-than-average season, which is forecast in the northern U.S. and the U.K. Even an ordinary cold season can pose a threat to human health and safety. One 2015 study published in the Lancet analyzed over 74 million deaths around the world found that more than 7% of deaths were attributed to exposure to cold temperatures. “There is conclusive evidence that there is increased risk for many health ou...
Source: TIME: Health - November 15, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized healthscienceclimate Public Health Wellbeing Source Type: news

New data buoy hopes for promising malaria vaccine —but questions remain
A new vaccine against malaria showed promising preliminary results in a large trial in four African countries, boosting hopes that an additional tool may soon be available to help control the deadly disease. The vaccine, named R21/Matrix-M and developed by researchers at the University of Oxford, produced similarly impressive results in a small trial last year , but the current study posed a stiffer test of its protection. Initial data from the trial, reported yesterday at the American Society of Tropical Medicine and Hygiene meeting in Seattle, suggest the vaccine had an efficacy higher than 70% in...
Source: ScienceNOW - November 3, 2022 Category: Science Source Type: news

Why you do not need to shower each morning, according to a hygiene expert
Professor Sally Bloomfield, a hygiene expert at the London School of Hygiene and Tropical Medicine, said showering and bathing regularly is only needed to ward off bad body odour. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2022 Category: Consumer Health News Source Type: news

Antibody weapon against malaria shows promise in Africa
A new way to prevent malaria that showed promise in 9 U.S. volunteers deliberately exposed to parasite-laden mosquitoes last year has now shown its mettle in a real-world situation in Africa. A study published today in the New England Journal of Medicine showed that a single dose of lab-produced monoclonal antibodies can protect recipients from infection for up to 6 months during Mali’s intense malaria season. Monoclonal antibodies are expensive to produce and can be cumbersome to administer if they are infused straight into the bloodstream. That makes some researchers skeptical that the new one...
Source: ScienceNOW - November 1, 2022 Category: Science Source Type: news

NHS blood amber alert: £2-a-pop drug 'could help ease dire blood shortage crisis'
Professor Ian Roberts, an epidemiologist at the London School of Hygiene and Tropical Medicine, told MailOnline tranexamic acid could be a 'major part of the solution' to England's blood shortage. (Source: the Mail online | Health)
Source: the Mail online | Health - October 14, 2022 Category: Consumer Health News Source Type: news

Featured review: House modifications for preventing malaria
Installing mosquito screening over house windows and closing the gaps in house eaves can help reduce infection with Plasmodium parasites and the number of people with anaemia in the household, according to an updated Cochrane Review published this week. Householders can implement many of these house modifications themselves, providing a simple malaria prevention tool to complement existing vector control strategies.The review author team, from the UK, Spain, South Africa, and Malawi, included one randomized controlled trial (RCT) and six cluster-RCTs, and noted an additional six ongoing trials. Trials assessed screening of...
Source: Cochrane News and Events - October 7, 2022 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Can you solve it? A maths of a hypothetical new Covid variant
How would it spread?The UK ’s autumn Covid-19 booster programme is underway, with approximately 26 million people eligible to receive a jab over the next few months.Today ’s puzzle imagines a hypothetical new variant, and asks the solver to think about how it would spread. It was set by Professor Adam Kucharski of the London School of Hygiene and Tropical Medicine, one of the UK’s leading epidemiologists.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - September 19, 2022 Category: Science Authors: Alex Bellos Tags: Mathematics Education Science Source Type: news