Glomerular filtration rate decline in T2DM following diagnosis. The Verona Newly Diagnosed Diabetes Study-12

Diabetic nephropathy is a common complication of type 2 diabetes (T2DM) [1] and its clinical consequences, such as chronic kidney disease (CKD), nephrotic syndrome, end-stage renal disease (ESRD) and cardiovascular disease (CVD), may be severe and life threatening [2,3]. Therefore, it is important to timely identify patients with incipient nephropaty or at high risk of marked loss of renal function in order to implement strategies to stop or slow down the progression of the disease. Increased albuminuria and reduced glomerular filtration rate (GFR) are the classic biomarkers of nephropathy, and its progression is heralded by significant changes in these two parameters [4,5].

Source: Diabetes Research and Clinical Practice - March 22, 2021 Category: Endocrinology Authors: Giacomo Zoppini, Maddalena Trombetta, Ilaria Pastore, Corinna Brangani, Vittorio Cacciatori, Carlo Negri, Fabrizia Perrone, Isabella Pichiri, Vincenzo Stoico, Daniela Travia, Elisabetta Rinaldi, Giuliana Da Prato, Cristina Bittante, Riccardo C. Bonadonna, Source Type: research