MicroRNA expression changes following BCL11A inhibition in CD34+-derived red blood cells

CONCLUSIONS: The expression levels of miR-15a, miR-16, miR-23a, miR-27a, and miR-486 changed before and after γ-to-β gene switching. Therefore, this may be an effective intervention for controlling the switching and synthesis of fetal hemoglobin.PMID:33707350 | DOI:10.5045/br.2021.2020087

Source: Blood Research - March 12, 2021 Category: Hematology Authors: Narges Obidi Fatemeh Saberi Asad Taghavi Reza Ranjbaran Gholamreza Khamisi Pour Gholamhossein Tamaddon Source Type: research