Systemic microvascular endothelial dysfunction is associated with left ventricular ejection fraction reduction in chronic Chagas disease patients

ConclusionsWe have shown for the first time that the reduction of MR is associated with a decrease of LVEF in a cohort of chronic CD patients. The results were not affected by comorbidities, such as hypertension or diabetes. The evaluation of systemic endothelial function may be useful to tailor therapeutic and preventive approaches, targeted at systolic left ventricular failure associated with chronic CD cardiomyopathy.

Source: Microcirculation - March 1, 2021 Category: Research Authors: Daniel Arthur Barata Kasal, Ademar Britto, Val éria Verri, Andrea De Lorenzo, Eduardo Tibirica Tags: ORIGINAL RESEARCH Source Type: research