Differential expression of < em > COL4A3 < /em > and collagen in upward and downward progressing types of nasopharyngeal carcinoma

In conclusion, the gene mutation patterns were significantly different between the upward and downward progressing types of NPC. In addition, the expression level of the COL4A3 gene was decreased in the downward progressing type, which might promote NPC metastasis through the downregulation of extracellular collagen expression.PMID:33613712 | PMC:PMC7859474 | DOI:10.3892/ol.2021.12484
Source: Oncology Letters - Category: Cancer & Oncology Authors: Source Type: research