Defining the index lesion for potential salvage partial or hemi-gland ablation after radiation therapy for localized prostate cancer

CONCLUSIONS: In men with recurrent prostate cancer after radiotherapy, biopsy findings and MRI can be used to select index lesions potentially amenable for sPGA and can guide patient evaluation for inclusion in clinical trials of sPGA following radiation failure. Larger, prospective studies are required to evaluate both the role of MRI and clinical criteria in guiding focal salvage therapy and the effectiveness of this modality for radiorecurrent prostate cancer.PMID:33583697 | DOI:10.1016/j.urolonc.2021.01.011

Source: Urologic Oncology - February 15, 2021 Category: Urology & Nephrology Authors: Gregory T Chesnut Amy L Tin Arjun Sivaraman Toshikazu Takeda Taehyoung Lee Jonathan Fainberg Nicole Benfante Daniel D Sjoberg Hebert Alberto Vargas Samson W Fine Peter T Scardino James A Eastham Jonathan A Coleman Karim A Touijer Michael J Zelefsky Behfar Source Type: research