Genistein exerts a cell-protective effect via Nrf2/HO-1/PI3K signaling in A β25-35-induced Alzheimer's disease models in vitro.

CONCLUSIONS: These results suggest that genistein exerts a neuroprotective effect on SH-SY5Y cells in vitro via Nrf2/HO-1/PI3K signaling, providing a foundation for the application of genistein in the treatment of neurodegenerative diseases related to Nrf2/HO-1/PI3K signaling. PMID: 33605427 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33605427?dopt=Abstract

Source: Folia Histochemica et Cytobiologica - February 21, 2021 Category: Cytology Tags: Folia Histochem Cytobiol Source Type: research