A Novel RELA Truncating Mutation in a Familial Beh çet’s Disease–like Mucocutaneous Ulcerative Condition

ConclusionOur data indicate that RELA loss ‐of‐function mutations cause BD‐like autoinflammation and NMO via impaired NF‐κB signaling and increased apoptosis.

Source: Arthritis and Rheumatology - February 15, 2021 Category: Rheumatology Authors: Fahd Adeeb, Emma R. Dorris, Niamh E. Morgan, Dylan Lawless, Aqeel Maqsood, Wan Lin Ng, Orla Killeen, Eoin P. Cummins, Cormac T. Taylor, Sinisa Savic, Anthony G. Wilson, Alexander Fraser Tags: Brief Report Source Type: research