Combined Effect of Mediterranean Diet and Aerobic Exercise on Weight Loss and Clinical Status in Obese Symptomatic Patients with Hypertrophic Cardiomyopathy

We evaluated the impact of weight loss (WL) using a Mediterranean diet and mild-to-moderate –intensity aerobic exercise program, on clinical status of obese, symptomatic patients with hypertrophic cardiomyopathy (HCM). Compared with nonresponders, responders showed a significant reduction of left atrial diameter, left atrial volume index (LAVI), E/Eʹaverage, pulmonary artery systolic pr essure (PASP), and a significant increase in Vo2max (%) and peak workload. Body mass index changes correlated with reduction in left atrial diameter, LAVI, E/Eʹaverage, PASP, and increase of Vo2max (mL/Kg/min), Vo2max (%), peak workload. Mediterranean diet and aerobic exercise is associated with cl inical-hemodynamic improvement in obese symptomatic HCM patients.

Source: Heart Failure Clinics - February 10, 2021 Category: Cardiology Authors: Giuseppe Limongelli, Emanuele Monda, Antonello D ’Aponte, Martina Caiazza, Marta Rubino, Augusto Esposito, Giuseppe Palmiero, Elisabetta Moscarella, Giovanni Messina, Paolo Calabro’, Olga Scudiero, Giuseppe Pacileo, Marcellino Monda, Eduardo Bossone, Source Type: research