Severe skin toxicity during whole-brain radiotherapy, targeted therapy, and additional drug intake including St. John ’s wort skin oil

ConclusionSt. John ’s wort seems to be a significant radiosensitizer for photon radiotherapy and can cause severe skin toxicity even though the literature lacks data on this interaction. As an OTC, it is easily accessible and often used by oncological patients due to antidepressant and local antimicrobial and pain- relieving effects.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research