Ivermectin presents effective and selective antileishmanial activity in vitro and in vivo against Leishmania infantum and is therapeutic against visceral leishmaniasis.

In conclusion, results suggest that IVE/Mic could be considered in future studies as a therapeutic alternative to treat VL.
PMID: 33338468 [PubMed - as supplied by publisher]

Source: Experimental Parasitology - December 15, 2020 Category: Parasitology Authors: Reis TAR, Oliveira-da-Silva JA, Tavares GSV, Mendonça DVC, Freitas CS, Costa RR, Lage DP, Martins VT, Machado AS, Ramos FF, Silva AM, Ludolf F, Antinarelli LMR, Brito RCF, Chávez-Fumagalli MA, Humbert MV, Roatt BM, Coimbra ES, Coelho EAF Tags: Exp Parasitol Source Type: research