Overweight/obesity in young adulthood interacts with aspects of EBV infection in MS etiology

Conclusions With regard to MS risk, overweight/obesity in young adulthood acts synergistically with both aspects of EBV infection, predominantly among those with a genetic susceptibility to the disease. The obese state both induces a chronic immune-mediated inflammation and affects the cellular immune response to infections, which may contribute to explain our findings.

http://nn.neurology.org/cgi/content/short/8/1/e912?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - December 15, 2020 Category: Neurology Authors: Hedström, A. K., Brenner, N., Butt, J., Hillert, J., Waterboer, T., Olsson, T., Alfredsson, L. Tags: Multiple sclerosis Article Source Type: research