Overexpression of chloride importer NKCC1 contributes to the sensory-affective and sociability phenotype of rats following neonatal maternal separation.

CONCLUSIONS: This work suggests that an impaired chloride homeostasis, linked to oxytocin signaling dysfunction and to neuro-inflammatory processes, could contribute to the sensori-affective phenotype following NMS.
PMID: 33316378 [PubMed - as supplied by publisher]

Source: Brain, Behavior, and Immunity - December 11, 2020 Category: Neurology Authors: Gazzo G, Melchior M, Caussaint A, Gieré C, Lelièvre V, Poisbeau P Tags: Brain Behav Immun Source Type: research