An Update on COVID-19 Pandemic: The Epidemiology, Pathogenesis, Prevention and Treatment Strategies.

An Update on COVID-19 Pandemic: The Epidemiology, Pathogenesis, Prevention and Treatment Strategies. Expert Rev Anti Infect Ther. 2020 Dec 11;: Authors: Tsang HF, Chan LWC, Cho WCS, Yu ACS, Yim AKY, Chan AKC, Ng LPW, Wong YKE, Pei XM, Li MJW, Wong SCC Abstract INTRODUCTION: To date, the transmission of Coronavirus Disease-2019 (COVID-19) is still overwhelming with the fact that numbers of confirmed cases and deaths keep increasing. As of 1 October, 2020, 33,842,281 confirmed cases and 1,010,634 confirmed deaths have been reported to the World Health Organization from 216 countries. Despite the urgent need of effective treatment strategies, there is no specific antiviral treatment for COVID-19 currently and the treatment guidelines for COVID-19 vary among countries. AREA COVERED: In this article, we summarized the current knowledge about the causative pathogen and the pandemic worldwide. The epidemiology, pathogenesis, prevention and various treatment options of COVID-19 will be discussed for better acknowledgment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). EXPERT OPINION: The situation of the COVID-19 pandemic is still unpredictable. There is no effective vaccine or specific anti-viral drug to treat serve COVID-19 patients. Combination therapies such as a triple combination of interferon beta-1b, lopinavir-ritonavir and ribavirin or hydroxychloroquine plus azithromycin have shown promising clinica...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research