Renin profiling predicts neurohormonal response to sacubitril/valsartan

ConclusionsIn our preliminary study, we show that circulating renin predicts reduction in NT ‐proBNP levels after sacubitril/valsartan initiation in HFrEF patients. Renin assessment might be useful to discriminate potential responders from the subgroup with a weaker expected benefit, thus needing a closer, tailored management strategy.

https://onlinelibrary.wiley.com/doi/abs/10.1002/ehf2.13085?af=R

Source: ESC Heart Failure - November 20, 2020 Category: Cardiology Authors: Giuseppe Vergaro, Paolo Sciarrone, Concetta Prontera, Silvia Masotti, Veronica Musetti, Alessandro Valleggi, Alberto Giannoni, Michele Senni, Michele Emdin, Claudio Passino Tags: Short Communication Source Type: research