Metformin promotes susceptibility to experimental Leishmania braziliensis infection.

CONCLUSION: Experimental treatment with MET interfered with the kinetics of cutaneous ulceration, increased Lb parasite load, altered ROS production and modulated cellular proliferation. Our experimental results indicate that MET interfere with the evolution of CL. PMID: 33206822 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/33206822?dopt=Abstract

Source: Memorias do Instituto Oswaldo Cruz - November 20, 2020 Category: Infectious Diseases Authors: Lima FR, Ferreira LM, Malta TA, Bonyek-Silva I, Santos RL, Tavares NM, Carvalho Filho EM, Arruda S Tags: Mem Inst Oswaldo Cruz Source Type: research