Metformin alleviates hydrogen peroxide-induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons.

In conclusion, our results show that metformin can alleviate H2O2-induced inflammation and oxidative stress via modulating the P2X7R signaling pathway. PMID: 33201730 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33201730?dopt=Abstract

Source: Canadian Journal of Physiology and Pharmacology - November 17, 2020 Category: Drugs & Pharmacology Authors: Wang G, Chen S, Shao Z, Li Y, Wang W, Mao L, Li J, Mei X Tags: Can J Physiol Pharmacol Source Type: research