Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress.

CONCLUSIONS: Obesity is associated with significant changes in RBC metabolism and increased susceptibility to hemolysis under routine storage of RBC units. The impact on transfusion efficacy warrants further evaluation.
PMID: 33146433 [PubMed - as supplied by publisher]

Source: Transfusion - November 4, 2020 Category: Hematology Authors: Hazegh K, Fang F, Bravo MD, Tran JQ, Muench MO, Jackman RP, Roubinian N, Bertolone L, DʼAlessandro A, Dumont L, Page GP, Kanias T Tags: Transfusion Source Type: research