Evaluation of patients with primary immunodeficiency associated with Bacille Calmette-Guerin (BCG)-vaccine-derived complications.

CONCLUSION: The high rate of undiagnosed PIDs predisposes individuals to a high risk of severe side effects as a result of BCG vaccination, as well as infants that are less than one month of age. Therefore, there is a need for early screening and diagnosis of PIDs before exposing unknown PID status patients to BCG vaccination. The benefits of screening and early diagnosis of PID cannot be overemphasized, especially in patients with a previous family history of immunodeficiency. PMID: 33115608 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33115608?dopt=Abstract

Source: Allergologia et Immunopathologia - October 25, 2020 Category: Allergy & Immunology Authors: Sohani M, Habibi S, Delavari S, Shahkarami S, Yazdani R, Shirmast P, Nazari F, Shad TM, Mamishi S, Azizi G, Anka AU, Hassanpour G, Kalantari A, Shariat M, Shafiei A, Abolhassani H, Aghamohammadi A Tags: Allergol Immunopathol (Madr) Source Type: research