Consequences of Supraphysiological Dialysate Magnesium on Arterial Stiffness, Hemodynamic Profile, and Endothelial Function in Hemodialysis: A Randomized Crossover Study Followed by a Non-Controlled Follow-Up Phase

ConclusionsIncreasing dialysate magnesium improves vascular stiffness in subjects undergoing maintenance hemodialysis. The present findings merit a larger trial to evaluate the effects of 0.75  mmol/L D-Mg2+ on major clinical outcomes.Trial RegistrationThe study was retrospectively registered on the ISRCTN registry (ISRCTN 74139255) on 18 June 2020.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research