The heart of the matter at molecular level

At the molecular level two potentially modifiable risk factor for worsening of congestive heart failure(CHF) have now been brought to the attention of clinicians dealing with the syndrome of CHF. Iron deficiency(ID), with or without anaemia, is one such risk factor [1,2]. In the prospective study by Kleber et al., mortality risk was evaluated in 455 CHF patients who had been diagnosed with ID using the criterion of mean corpuscular haemoglobin concentration of 330  g/L or less. In comparison with 1119 iron-replete CHF counterparts, the ID subgroup were characterised by increased mortality(Hazard Ratio 1.7, 95% Confidence Interval 1.4 to 2.0).

Source: The American Journal of Emergency Medicine - October 20, 2020 Category: Emergency Medicine Authors: Oscar M.P. Jolobe Source Type: research