Relationship between duration of heart failure, patient characteristics, outcomes, and effect of therapy in PARADIGM ‐HF

ConclusionsPatients with longer ‐duration HF had more co‐morbidity, worse quality of life, and higher rates of HF hospitalization and death. The benefit of a neprilysin inhibitor was consistent, irrespective of HF duration. Switching to sacubitril/valsartan had substantial benefits, even in patients with long‐standing HF.

Source: ESC Heart Failure - October 19, 2020 Category: Cardiology Authors: Su E. Yeoh, Pooja Dewan, Akshay S. Desai, Scott D. Solomon, Jean L. Rouleau, Marty Lefkowitz, Adel Rizkala, Karl Swedberg, Michael R. Zile, Pardeep S. Jhund, Milton Packer, John J.V. McMurray Tags: Original Research Article Source Type: research