Solitary chemosensory cells are innervated by trigeminal nerve endings and autoregulated by cholinergic receptors
ConclusionSCCs are innervated by trigeminal nerve endings in healthy turbinate tissue but not in NPs. SCCs express ACh receptors as well as choline acetyltransferase and, in the setting of a type 2 inflammatory environment, denervated SCCs dramatically expand with nicotinic stimulation.
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Jie Deng,
Li Hui Tan,
Michael A. Kohanski,
David W. Kennedy,
John V. Bosso,
Nithin D. Adappa,
James N. Palmer,
Jianbo Shi,
Noam A. Cohen Tags: ORIGINAL ARTICLE Source Type: research
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