Epidemiological Situation and Efficacy of Dexamethasone for the treatment planning of COVID-19: A perspective review.

Epidemiological Situation and Efficacy of Dexamethasone for the treatment planning of COVID-19: A perspective review. Curr Drug Deliv. 2020 Oct 06;: Authors: Wahab S, Ahmad I, Usmani S, Ahmad MP Abstract The current COVID-19 pandemic has prompted the urgent requirement for searching effective treatments since the implications are so huge globally as compared to the earlier pandemics. Momentarily, there has been no effective medicine for SARS-CoV-2 infection, and supportive care tends to be the most effective approach to treat COVID-19 patients. The rapidly growing awareness of SARS-CoV-2 virology offers a large number of possible drug targets. The World Health Organisation (WHO) is steadily updating the treatment protocol for COVID-19 based on the recent clinical trials. In the present review, we have summarised the possible mode of action, clinical evidence, consequences of the dexamethasone as a therapeutic agent against Covid-19. Currently, there are many corticosteroids tested in ongoing randomised trials. Dexamethasone could come as a lifesaving drug. Dexamethasone drug looks useful only in those patients who are already in a critical state. We might allow dexamethasone as a fascinating shot if the long-term health effects of Covid-19 recovered patients safeguard favourable clinical meanings. It is commonly accepted to reinforce approved drugs in the fight against newly emerging diseases such as COVID-19 as these drugs have established pharmacokinet...
Source: Current Drug Delivery - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Deliv Source Type: research

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Conclusions: Early results of universal preoperative screening for COVID-19 demonstrates a low incidence and high rate of asymptomatic patients. Health care professionals, especially those at higher risk for the virus, should be aware of the challenges related to screening based solely on symptoms or travel history and consider universal screening for patients undergoing elective surgery. Level of Evidence: Level II.
Source: Journal of Pediatric Orthopaedics - Category: Orthopaedics Tags: Infection Source Type: research
After being epidemic in China, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) infection has rapidly spread in many countries as a global pandemic, with the number of affected cases dramatically increasing worldwide on a daily basis. Although the median age of hospitalized patients with confirmed infection is usually more advanced 1, with older age reported to be associated to higher mortality rate 2, physiological adaptations occurring during pregnancy have been claimed to be potentially responsible for a more severe respiratory disease, thus leading to higher rates of maternal and fetal complications 3,4.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Correspondence Source Type: research
Steve Lindsay, a public health entomologist at Durham University, is midway through explaining how dogs might play a role in detecting COVID-19 infections when a decidedly less-well trained canine interrupts our conversation. “If you’ll excuse me for a minute, I’ve got a naughty black Labrador out in the back garden doing something it shouldn’t be doing,” Lindsay says. He disappears. I hear barking. He returns accompanied by a chocolate lab. “She’s not as skilled as the detection dogs,” Lindsay says as the pup tries to lick his face. “But it’s really interesting t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Conditions:   Cancer;   COVID-19 Intervention:   Sponsor:   Cancer Trials Ireland Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This article aims to present the first cohort of COVID-19 patients updated to Feb 28th, 2020 in Vietnam and sharing the national response to the pandemic. PMID: 33029087 [PubMed - in process]
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Authors: Batista RCS, Arruda CVB, Cassimiro M, Gominho L, Moura AC, Albuquerque DS, Romeiro K Abstract As early as December 2019 in the province of Hubei, China, contamination of patients with pneumonia of an unknown etiology occurred. These patients presented with symptoms such as coughing, sore throat, malaise, diarrhea, high fever, and dyspnea. This emerging disease was named COVID-19 due to being part of the group of coronaviruses (CoVs) belonging to the subfamily Orthocoronavirinae, in the Coronaviridae family and in the Nidovirales order. COVID-19 is most commonly transmitted through speech, coughing, sneezin...
Source: The Scientific World Journal - Category: Science Tags: ScientificWorldJournal Source Type: research
Most Brazilian state and municipal governments have used social distancing as the primary strategy for reducing the transmission speed of the new Coronavirus (SARS-CoV-2), which causes COVID-19. However, this social isolation has had several adverse reperc...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Since the appearance of the novel coronavirus (severe acute respiratory syndrome-coronavirus-2) and related coronavirus disease 2019 (COVID-19) in China in December 2019, a very high number of small and large patient series have been published in literature from around the world. Even though the classical presentation of COVID-19 is one with respiratory symptoms with or without pneumonia that can be self-limiting or evolve into severe respiratory distress syndrome with multiple organ failure, and secondary bacterial sepsis, a large body of evidence suggests a plethora of other types of clinical presentation. In this exhaus...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Conditions:   Cancer;   COVID-19 Intervention:   Sponsor:   Cancer Trials Ireland Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Pathology Autopsy and Mortuary Services have been front and center in the severe acute respiratory syndrome coronavirus 2 (SARS-Co-V-2) pandemic. The sheer number of fatalities from the pandemic have been unlike any other in recent memory and needed the rapid creation of new protocols and paradigms to manage the situation. This required rapidly escalating mortuary capacity to manage the increased fatalities from the pandemic with the establishment of lines of communication and networking with governmental entities, institution of new policies for patient flow, and implementation of worker infection control and well-being p...
Source: Advances in Anatomic Pathology - Category: Pathology Tags: Review Articles Source Type: research
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