Trump vs. Biden: what's at stake for science?

A conversation about the US election and the possible fallout for science, and are maternal behaviours learned or innate?In this episode:00:46 US electionIn the United States the presidential race is underway, and Nature is closely watching to see what might happen for science. We speak to two of our US based reporters to get their insight on the election and what to look out for. News Feature: A four-year timeline of Trump’s impact on science; News Feature: How Trump damaged science — and why it could take decades to recover; News: What a Joe Biden presidency would mean for five key science issues12:36 CoronapodWith news of the US President Donald Trump contracting coronavirus, the Coronapod team discuss the treatments he has received and what this might mean for the US government. News: Contact tracing Trump's travels would require 'massive' effort25:33 Research HighlightsHow binary stars could become black hole mergers, and a prehistoric massacre. Research Highlight: The odd couple: how a pair of mismatched black holes formed; Research Highlight: A bustling town’s annihilation is frozen in time27:36 Are parental behaviours innate?Nature versus nurture is a debate as old as science itself,and in a new paper maternal behaviours are innate or learned, by looking at the neurological responses of adult mice to distress calls from mice pups. Research Article: Schiavo et al.33:03 Briefing ChatThis week sees the announcement of the Nobel Prizes, so we chat about ...
Source: Nature Podcast - Category: Science Authors: Source Type: podcasts

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Kizzmekia Corbett joins TWiV to review her career and her work on respiratory syncytial virus, influenza virus, and coronaviruses and coronavirus vaccines, including her role in development and testing of a spike-encoding mRNA vaccine, and then we review the Nobel Prize for discovery of hepatitis C virus. Click arrow to playDownload TWiV 670 (76 MB .mp3, […]
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology coronavirus COVID-19 influenza virus mRNA-1273 pandemic prefusion conformation respiratory syncytial virus SARS-CoV-2 spike vaccine viral viruses Source Type: blogs
Honour given special resonance in year when world is gripped by coronavirus pandemic
Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news
(STOCKHOLM) — Americans Harvey J. Alter and Charles M. Rice and British-born scientist Michael Houghton won the Nobel Prize for medicine on Monday for their discovery of the hepatitis C virus, a major source of liver disease that affects millions worldwide. Announcing the prize in Stockholm, the Nobel Committee noted that the trio’s work identified a major source of blood-borne hepatitis that couldn’t be explained by the previously discovered hepatitis A and B viruses. Their work, dating back to the 1970s and 1980s, has helped saved millions of lives, the committee said. “Thanks to their discovery, ...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized News News Desk wire Source Type: news
Authors: Pokorska-Śpiewak M, Śpiewak M Abstract In recent years, significant progress in the antiviral treatment of chronic hepatitis C (CHC) has been made due to the development of interferon-free therapies. Three different highly effective, oral direct-acting antiviral (DAA) regimens have been approved for use in adolescents with CHC between the ages of 12-years-old and 17-years-old in Europe. According to the current recommendations, all treatment-naïve and treatment-experienced children with CHC virus infection should be considered for DAA therapy to prevent the possible progression of hepatitis C virus-...
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
F, Rizzo LV Abstract BACKGROUND: Coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) collection began in two Brazilian hospitals for treatment of severe/critical patients. METHODS AND MATERIALS: Mild/moderate COVID-19 convalescents were selected as CCP donors after reverse transcription polymerase chain reaction (RT-PCR) confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and absence of symptoms for ≥14 days plus (a) age (18-60 years), body weight greater than 55 kg; (b) immunohematological studies; (c) no infectious markers of hepatitis B virus, ...
Source: Transfusion - Category: Hematology Authors: Tags: Transfusion Source Type: research
Many types of viral infections can involve the human cardiovascular, such as Coxsackievirus, parvovirus B19, adenovirus, influenza virus, human herpes virus, Epstein-Barr virus, cytomegalovirus, hepatitis C virus, human immunodeficiency virus (HIV) [1], and even severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is currently circulating worldwide [2]. Zika virus (ZIKV), a type of RNA virus belonging to the family Flaviviridae and genus Flavivirus, was declared a Public Health Emergency of International Concern in February 2016 by the World Health Organization due to the severe damage it causes to the nervous system.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Tags: Letter to the editor Source Type: research
We report 10 candidates with optimal binding features to the active site of the protease for further consideration as potential drugs to treat patients infected with the emerging COVID-19 disease. PMID: 32773989 [PubMed]
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research
Vincent visits Ohio State University (March 2020) and speaks with Shan-Lu, David, Amanda, Mark, Matt, Chris, and Qiuhong about their careers and their work on retroviruses, hepatitis C virus, coronaviruses, paramyxoviruses, and environmental viruses. Click arrow to playDownload TWiV 650 (63 MB .mp3, 105 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology coronavirus COVID-19 hepatitis C virus HTLV pandemic plant viruses retrovirus SARS-CoV-2 viral viroids Source Type: blogs
AbstractBackground and AimCytokine storm has been reported in patients with coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. We examine the incidence of acute on chronic liver failure (ACLF) in COVID-19 patients with pre-existing compensated chronic liver disease (CLD).MethodsFrom 20 Jan 2020 to 7 Feb 2020, we studied 140 consecutive COVID-19 patients admitted to either Fuyang Second People ’s Hospital (FYSPH), Anhui or the Fifth Medical Center of Chinese PLA General Hospital (PLAGH) in Beijing, China. Pre-existing CLD includes those with liver cirrhos...
Source: Hepatology International - Category: Infectious Diseases Source Type: research
CONCLUSION: These promising drugs could inhibit the replication of the virus; hence, we suggest the repurposing of these compounds for thetreatment of COVID-19. No toxicity measurements are required for these drugs since they were previously tested prior to their approval by the FDA. However, the assessment of these potential inhibitors as clinical drugs involves further in vivo tests for these drugs. PMID: 32748740 [PubMed - as supplied by publisher]
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Tags: Comb Chem High Throughput Screen Source Type: research
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