Role of a Pediatric Cardiologist in the COVID-19 Pandemic

AbstractCoronavirus disease 2019 (COVID-19) has affected patients across all age groups, with a wide range of illness severity from asymptomatic carriers to severe multi-organ dysfunction and death. Although early reports have shown that younger age groups experience less severe disease than older adults, our understanding of this phenomenon is in continuous evolution. Recently, a severe multisystem inflammatory syndrome in children (MIS-C), with active or recent COVID-19 infection, has been increasingly reported. Children with MIS-C may demonstrate signs and symptoms of Kawasaki disease, but also have some distinct differences. These children have more frequent and severe gastrointestinal symptoms and are more likely to present with a shock-like presentation. Moreover, they often present with cardiovascular involvement including myocardial dysfunction, valvulitis, and coronary artery dilation or aneurysms. Here, we present a review of the literature and summary of our current understanding of cardiovascular involvement in children with COVID-19 or MIS-C and identifying the role of a pediatric cardiologist in caring for these patients.
Source: Mammalian Genome - Category: Genetics & Stem Cells Source Type: research

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We present 4 patients along with their emergency department course, so providers will have a better understanding of the identification and workup of these patients. Currently, it is unclear when this inflammatory syndrome develops in respect to a COVID-19 infection. The clinical features of this syndrome seem to overlap between Kawasaki disease, toxic shock syndrome, and myocarditis. All patients presenting to our emergency department had fever, variable rash, abdominal pain, vomiting, and/or diarrhea. Patients remained persistently tachycardic and febrile despite being given proper doses of antipyretics. Severity of pres...
Source: Pediatric Emergency Care - Category: Emergency Medicine Tags: Special Features Source Type: research
Authors: Bertoli F, Veritti D, Danese C, Samassa F, Sarao V, Rassu N, Gambato T, Lanzetta P Abstract The novel pandemic coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has challenged the medical community. While diagnostic and therapeutic efforts have been focused on respiratory complications of the disease, several ocular implications have also emerged. SARS-CoV-2 RNA has been found in tears of the infected patients, and reports suggest that the ocular surface could serve as a portal of entry and a reservoir for viral transmission. Clinically, COVID-...
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Conclusions: Pediatric COVID-19 and its potential association to severe KD, still unfamiliar to heal th professionals, reinforces the importance of testing patients with vasculitis for the new coronavirus and the need to wage high surveillance and preparation of the health system during the current pandemic.RESUMO Objetivo: Analisar a literatura cient ífica atual a fim de documentar, por meio de revisão integrativa, os principais achados que associam a doença de Kawasaki (DK) à doença do coronavírus (COVID-19). Fonte de dados: A busca ocorreu em junho de 2020, nas bases de dados: B...
Source: Revista Paulista de Pediatria - Category: Pediatrics Source Type: research
rapcak S, Datta D, Morris SB, Clarke K, Belay E, California MIS-C Response Team Abstract In April 2020, during the peak of the coronavirus disease 2019 (COVID-19) pandemic in Europe, a cluster of children with hyperinflammatory shock with features similar to Kawasaki disease and toxic shock syndrome was reported in England* (1). The patients' signs and symptoms were temporally associated with COVID-19 but presumed to have developed 2-4 weeks after acute COVID-19; all children had serologic evidence of infection with SARS-CoV-2, the virus that causes COVID-19 (1). The clinical signs and symptoms present in this fir...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Children represent a small proportion of the total number of confirmed cases, with older adults and those with underlying co-morbidities particularly affected by the current global pandemic. Whilst this is reassuring for paediatricians, there are limited data on childhood SARS-CoV-19 infections, especially from Europe. 28 July 2020 Added updated sKIDs protocol. 12 June 2020 Added studies 5 to 7: RAPID-19 study; sKIDs COVID-19 surveillance in school children; and Multi-system inflammatory syndrome, Kawasaki disease and toxic shock syndrome.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
We read with interest the well-founded observation made by Yung et al regarding no change in epidemiology or cases of Kawasaki disease in Singapore amid the current ongoing SARS-Coronavirus-2 pandemic. When it was initially recognized, there was uncertainty whether the SARS-CoV-2 associated multisystem inflammatory syndrome in children (MIS-C) represented Kawasaki disease. Evidence and evolving understanding suggest it to be a separate clinical entity.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Letters to the Editor Source Type: research
(Reuters Health)—During the COVID-19 pandemic, an inflammatory condition similar to Kawasaki disease has been reported in children and adolescents, and now two groups of New York doctors each describe a case, one in a 36-year-old woman and one in a 45-year-old man.1 “We’re still learning how COVID-19 is affecting children and adults. The better we... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Conditions adult coronavirus COVID-19 Kawasaki disease Source Type: research
Abstract The pandemic of COVID-19 initially appeared to cause only a mild illness in children. However, it is now apparent that a small percentage of children can develop a hyperinflammatory syndrome labeled as Pediatric inflammatory multisystem syndrome - temporally associated with SARS-CoV-2 (PIMS-TS). Features of this newly recognized condition may include persistent fever, evidence of inflammation, and single or multi organ dysfunction in the absence of other known infections. Some of these children may share features of Kawasaki disease, toxic shock syndrome or cytokine storm syndrome. They can deteriorate ra...
Source: Indian Pediatrics - Category: Pediatrics Authors: Tags: Indian Pediatr Source Type: research
By SAURABH JHA, MD The COVID-19 pandemic has been a testing time for the already testy academic discourse. Decisions have had to be made with partial information. Information has come in drizzles, showers and downpours. The velocity with which new information has arrived has outstripped our ability to make sense of it. On top of that, the science has been politicized in a polarized country with a polarizing president at its helm. As the country awoke to an unprecedented economic lockdown in the middle of March, John Ioannidis, professor of epidemiology at Stanford University and one of the most cited physician sc...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: COVID-19 Health Policy Public Health John Ioannidis Saurabh Jha Source Type: blogs
Paolo Ferrero, Isabelle Piazza, Caterina Bonino, Matteo CiuffredaAnnals of Pediatric Cardiology 2020 13(3):230-233 There is limited information about coronavirus disease 2019 (COVID-19) in the pediatric population. Preliminary data suggest a not insignificant prevalence of cardiac involvement. Here, we report our early experience with COVID-19 in the pediatric population. These patients display exceptionally high levels of acute-phase reactants. The clinical syndrome in these patients is somewhat similar to Kawasaki disease with or without myocardial involvement. In some cases, the presentation mimics typical myocarditis....
Source: Annals of Pediatric Cardiology - Category: Cardiology Authors: Source Type: research
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