C5aR1 is a master regulator in Colorectal Tumorigenesis via Immune modulation

Conclusion: Our study identifies C5a/C5aR1 signaling as a vital immunomodulatory program in CRC tumorigenesis and suggests a feasible preventive strategy.

Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Peipei Ding, Ling Li, Luying Li, Xinyue Lv, Danlei Zhou, Qingkai Wang, Jianfeng Chen, Chaoqun Yang, Enjie Xu, Weixing Dai, Xin Zhang, Na Wang, Qi Wang, Wei Zhang, Long Zhang, Yuzhen Zhou, Hongyu Gu, Qunying Lei, Xuhui Zhou, Weiguo Hu Tags: Research Paper Source Type: research