A Randomized Pilot Clinical Trial of Early Coronary Angiography Versus No Early Coronary Angiography for Post-Cardiac Arrest Patients Without ST-Segment Elevation: The PEARL Study.

Conclusions: This underpowered study, when considered together with previous clinical trials, does not support early coronary angiography for comatose survivors of cardiac arrest without ST elevation. Whether early detection of occluded potential culprit arteries leads to interventions that improve outcomes requires additional study. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT02387398. PMID: 32985249 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32985249?dopt=Abstract

Source: Circulation - September 27, 2020 Category: Cardiology Authors: Kern KB, Radsel P, Jentzer JC, Seder DB, Lee KS, Lotun K, Janardhanan R, Stub D, Hsu CH, Noc M Tags: Circulation Source Type: research